Results 161 to 170 of about 1,643,786 (267)

Mapping Fusarium wilt and sterility mosaic disease resistance-associated genomic regions and haplotype variants in pigeonpea. [PDF]

BMC Plant Biol
Rangari SK, Krishnappa S, Sharma M, Sharma VK, Lohithaswa HC, Dube N, Gangurde SS, Sharma V, Abbai R, Bomma N, Belliappa S, Bhutia KL, Thudi M, Gangashetty PI, Pandey MK.   +14 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance. [PDF]

Adv Sci (Weinh)
Kumar V, Kumara VIPWA, Bandaranayake PCG, Yawen D, Gao YY, Liu J, Hao GF, Xin XF.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Dietary Matrine Supplementation Enhances Growth, Immunity and Disease Resistance in Nile Tilapia (<i>Oreochromis niloticus</i>). [PDF]

Animals (Basel)
Luo S, Liang Y, Wang C, Zhai Y, Guo X, Zhang S, Zhang E, Yang D, Guo D, Liu T, Wang G, Wang E.   +11 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Leaf Developmental Stage Influences Disease Resistance in Tomato. [PDF]

Mol Plant Pathol
Lindner N, Leibman-Markus M, Gupta R, Anand G, Marash I, Dolgov T, Kleiman M, Bar M.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Genome editing and regeneration pipeline for engineering disease resistance in tomato using CRISPR/Cas9. [PDF]

Front Plant Sci
Erdoğan İ, Debbarma R, Sherry M, Mancak İ, Grant M, Tör M.   +5 more
europepmc   +1 more source