Results 171 to 180 of about 8,489,060 (313)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Advances in Genome Editing for Plant Disease Resistance Breeding. [PDF]

Plants (Basel)
Amoroso CG, Andolfo G.
europepmc   +1 more source

The role of photoprotection in disease resistance to Septoria tritici blotch in wheat

, 2019
Septoria tritici blotch (STB) caused by the fungus Zymoseptoria tritici is an important foliar disease of wheat in the UK. Symptoms of chlorotic and necrotic lesions with pycnidia appear on leaves 7-14 days after infection when the disease reduces plant ...
Kanyuka, K., Murchie, E., Ray, R., Angelopoulou, D.   +3 more
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Corrigendum to “A next-generation probiotic strain for gut health: Bacteroides cellulosilyticus LYH2 variant with anti-inflammatory and metabolic advantages” [EBioMedicine 126 (2026) 106232]

EBioMedicine
Cong Lan, Xiaofeng Deng, Shen Jin, Hua Li, Yang Liu, Aimin Wu, Yanjiao Liu, Yifan Zhang, Jun He, Zhaolai Dai, Daiwen Chen, Bing Yu, Zhiqing Huang, Xiangbing Mao, Ping Zheng, Jie Yu, Junqiu Luo, Hui Yan, Yuheng Luo   +18 more
doaj   +1 more source

Chlorogenic Acid Improves Intestinal Development via Suppressing Mucosa Inflammation and Cell Apoptosis in Weaned Pigs

ACS Omega, 2018
Jiali Chen, Hongmei Xie, Daiwen Chen, Bing Yu, Xiangbing Mao, Ping Zheng, Jie Yu, Yuheng Luo, Junqiu Luo, Jun He   +9 more
doaj   +1 more source

Editorial: Omics applications for pathogen control and disease resistance. [PDF]

Front Plant Sci
Rauwane M, Ngara R, Chikere CB, Ntushelo K.   +3 more
europepmc   +1 more source

Physiology of Disease Resistance in Plants [PDF]

Nature, 1948
W, BROWN, F T, BROOKS, F C, BAWDEN
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Machine learning empowers precise discovery of disease-resistance genes in plants. [PDF]

Plant Physiol
Liu Z, Wang X, Cao S, Lei T, Chen Z, Zhang M, Liu Z, Li J, Lu J, Ma W, Su B, Peng Y, Xu Y, Xu X, Zhang W, Tan C, Chen C, Wang Y, Zhou Y.   +18 more
europepmc   +1 more source