Results 41 to 50 of about 1,401,245 (290)

Effects of a Novel Protease on Growth Performance, Nutrient Digestibility and Intestinal Health in Weaned Piglets

Animals, 2022
This experiment was conducted to evaluate the effects of different protease levels on performance, diarrhea rate, nutrient digestibility, blood metabolites, digestive enzyme activities, and intestinal health of weaned piglets.
Qingqing Zhu, Yuxin Wang, Yanjie Liu, Bing Yu, Jun He, Ping Zheng, Xiangbing Mao, Zhiqing Huang, Junqiu Luo, Yuheng Luo, Hui Yan, Jie Yu   +11 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Exogenous Abscisic Acid Affects the Heat Tolerance of Rice Seedlings by Influencing the Accumulation of ROS

Antioxidants, 2023
Heat stress (HS) has become one of the major abiotic stresses that severely constrain rice growth. Abscisic acid (ABA) plays an important role in plant development and stress response.
Yingfeng Wang, Bin Lei, Huabing Deng, Xiong Liu, Yating Dong, Wenjuan Chen, Xuedan Lu, Guihua Chen, Guilian Zhang, Wenbang Tang, Yunhua Xiao   +10 more
doaj   +1 more source

A Data-Validated Host-Parasite Model for Infectious Disease Outbreaks [PDF]

, 2019
The use of model experimental systems and mathematical models is important to further understanding of infectious disease dynamics and strategize disease mitigation. Gyrodactylids are helminth ectoparasites of teleost fish which have many dynamical characteristics of microparasites but offer the advantage that they can be quantified and tracked over ...
arxiv   +1 more source

Mechanical resistance in unstructured proteins [PDF]

Biophysical Journal, Volume 104, Issue 12, 2725-2732, 18 June 2013, 2013
Single-molecule pulling experiments on unstructured proteins linked to neurodegenerative diseases have measured rupture forces comparable to those for stable folded proteins. To investigate the structural mechanisms of this unexpected force resistance, we perform pulling simulations of the amyloid {\beta}-peptide (A{\beta}) and {\alpha}-synuclein ...
arxiv   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Endoplasmic Reticulum Stress Contributes to Intestinal Injury in Intrauterine Growth Restriction Newborn Piglets

Animals
Intrauterine growth retardation (IUGR) in piglets is associated with a high rate of morbidity and mortality after birth due to gut dysfunction, and the underlying mechanisms remain poorly understood.
Tingting Fang, Gang Tian, Daiwen Chen, Jun He, Ping Zheng, Xiangbing Mao, Hui Yan, Bing Yu   +7 more
doaj   +1 more source

Dietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling

Journal of Animal Science and Biotechnology, 2022
Background Consumption of resistant starch (RS) has been associated with various intestinal and systemic health benefits, but knowledge of its effects on intestinal health and inflammatory response in stressed birds is limited.
Simeng Qin, Weiqiang Bai, Todd J. Applegate, Keying Zhang, Gang Tian, Xuemei Ding, Shiping Bai, Jianping Wang, Li Lv, Huanwei Peng, Yue Xuan, Quifeng Zeng   +11 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Deterministic and Stochastic in-host Tuberculosis Models for Bacterium-directed and Host-directed Therapy Combination [PDF]

arXiv, 2021
Mycobacterium tuberculosis infection can involve all immune system components and can result in different disease outcomes. The antibiotic TB drugs require strict adherence to prevent both disease relapse and mutation of drug- and multidrug-resistant strains.
arxiv