Results 41 to 50 of about 1,587,717 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs

EMBO Reports
Bacteria have evolved numerous biochemical processes that underpin their biology and pathogenesis. The small, non-enzymatic bacterial (Salmonella) effector SteE mediates kinase reprogramming, whereby the canonical serine/threonine host kinase GSK3 gains ...
Ioanna Panagi, Janina H Muench, Alexi Ronneau, Ines Diaz-del-Olmo, Agnel Aliyath, Xiu-Jun Yu, Hazel Mak, Enkai Jin, Jingkun Zeng, Diego Esposito, Elliott Jennings, Timesh D Pillay, Regina A Günster, Sarah L Maslen, Katrin Rittinger, Teresa L M Thurston   +15 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Endoplasmic Reticulum Stress Contributes to Intestinal Injury in Intrauterine Growth Restriction Newborn Piglets

Animals
Intrauterine growth retardation (IUGR) in piglets is associated with a high rate of morbidity and mortality after birth due to gut dysfunction, and the underlying mechanisms remain poorly understood.
Tingting Fang, Gang Tian, Daiwen Chen, Jun He, Ping Zheng, Xiangbing Mao, Hui Yan, Bing Yu   +7 more
doaj   +1 more source

Yeast hydrolysate attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage in weaned piglets

Journal of Animal Science and Biotechnology, 2023
Background Intestinal inflammation is the main risk factor causing intestinal barrier dysfunction and lipopolysaccharide (LPS) can trigger inflammatory responses in various eukaryotic species. Yeast hydrolysate (YH) possesses multi-biological effects and
Runqi Fu, Chan Liang, Daiwen Chen, Gang Tian, Ping Zheng, Jun He, Jie Yu, Xiangbing Mao, Yuheng Luo, Junqiu Luo, Bing Yu   +10 more
doaj   +1 more source

Insulin Resistance Exacerbates Alzheimer Disease via Multiple Mechanisms [PDF]

, 2021
Zeng-Hui Wei, Jagadish Koya, Sandra E. Reznik   +2 more
openalex   +1 more source

Rifampin-resistant Meningococcal Disease

Emerging Infectious Diseases, 2005
Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide surveillance.
Jean Rainbow, Elizabeth Cebelinski, Joanne Bartkus, Anita Glennen, Dave Boxrud, Ruth Lynfield   +5 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Effects of High Ambient Temperature on Small Intestinal Morphology and Colonic Microbiota in Weaned Piglets

Animals, 2022
A total of 16 crossbred (Duroc × Landrace × Yorkshire) barrows, with an average initial body weight of 8.61 ± 0.24 kg (28 days of age), were randomly allotted into the control group (CON group) and high ambient temperature group (HT group) with 8 ...
Shuaibing Xing, Shuai Chen, Ying Zhao, Yuheng Luo, Bing Yu, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Junqiu Luo, Hui Yan, Jie Yu   +11 more
doaj   +1 more source

Recent Progress in Rice Broad-Spectrum Disease Resistance [PDF]

, 2021
Zhiquan Liu, Yu‐Jun Zhu, Huanbin Shi, Jiehua Qiu, Xinhua Ding, Yanjun Kou   +5 more
openalex   +1 more source