Results 61 to 70 of about 8,489,060 (313)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels

Journal of Animal Science and Biotechnology, 2018
Background Persistent lactation, as the result of mammary cellular anabolism and secreting function, is dependent on substantial mobilization or catabolism of body reserves under nutritional deficiency.
Heju Zhong, Peng Wang, Yumo Song, Xiaoling Zhang, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, Jian Li, De Wu, Qiaofeng Wu, Zhengfeng Fang   +11 more
doaj   +1 more source

A genome-wide genetic map of NB-LRR disease resistance loci in potato [PDF]

, 2011
Like all plants, potato has evolved a surveillance system consisting of a large array of genes encoding for immune receptors that confer resistance to pathogens and pests.
Erin Bakker, Gerard van der Linden, Rene Klein-Lankhorst, Eck, H.J., van, Arens, M.J.B., van Eck, H.J., Mariëlle Muskens, van der Ham, R., van der Vossen, E.A.G., Visser, R.G.F., Vossen, E.A.G., van der, Muskens, M., Jaap Bakker, Jan de Boer, Bakker, E.H., Theo Borm, Roeland van Ham, van der Linden, C.G., Prins, J.C.P., Vossen, J., Goverse, A., Richard Visser, Aska Goverse, Uenk, G.E., Herman van Eck, Geert Smant, Pjotr Prins, Borm, T.J.A., Ham, R., van der, Bakker, J., Edwin van der Vossen, Marjon Arens, Boer, J.M., de, Gerda Uenk, de Boer, J.M., Klein Lankhorst, R.M., Jack Vossen, Linden, C.G., van der   +37 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe, Giske CG, European Study Group on Antimicrobial Resistance Surveillance   +2 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Unlocking the power of swine gut bacteria: newly isolated Blautia strain and its metabolites inhibit the replication of Salmonella Typhimurium in macrophages and alleviate DSS-induced colitis in mice

Journal of Animal Science and Biotechnology
Background Inflammatory bowel disease is a significant health concern for both humans and large-scale farm animals. In the quest for effective alternatives to antibiotics, next-generation probiotics (NGPs) have emerged as a promising option.
Jiatong Wei, Yang Liu, Hua Li, Ze Lu, Yanjiao Liu, Yifan Zhang, Cong Lan, Aimin Wu, Jun He, Jingyi Cai, Gang Tian, Daiwen Chen, Bing Yu, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Hui Yan, Jiayong Tang, Huifen Wang, Quyuan Wang, Yuheng Luo   +22 more
doaj   +1 more source

Endoplasmic Reticulum Stress Contributes to Intestinal Injury in Intrauterine Growth Restriction Newborn Piglets

Animals
Intrauterine growth retardation (IUGR) in piglets is associated with a high rate of morbidity and mortality after birth due to gut dysfunction, and the underlying mechanisms remain poorly understood.
Tingting Fang, Gang Tian, Daiwen Chen, Jun He, Ping Zheng, Xiangbing Mao, Hui Yan, Bing Yu   +7 more
doaj   +1 more source

Rational consideration of Akkermansia muciniphila targeting intestinal health: advantages and challenges

npj Biofilms and Microbiomes, 2022
As one of the promising next-generation probiotics (NGPs), Akkermansia muciniphila, a well-known mucin-degrading bacterium, has been proven to be closely related to the metabolic diseases of its human host. However, the role of A. muciniphila in the host’
Yuheng Luo, Cong Lan, Hua Li, Qingyuan Ouyang, Fanli Kong, Aimin Wu, Zhihua Ren, Gang Tian, Jingyi Cai, Bing Yu, Jun He, André-Denis G. Wright   +11 more
doaj   +1 more source