Results 51 to 60 of about 8,964,528 (267)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels

Journal of Animal Science and Biotechnology, 2018
Background Persistent lactation, as the result of mammary cellular anabolism and secreting function, is dependent on substantial mobilization or catabolism of body reserves under nutritional deficiency.
Heju Zhong, Peng Wang, Yumo Song, Xiaoling Zhang, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, Jian Li, De Wu, Qiaofeng Wu, Zhengfeng Fang   +11 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Endoplasmic Reticulum Stress Contributes to Intestinal Injury in Intrauterine Growth Restriction Newborn Piglets

Animals
Intrauterine growth retardation (IUGR) in piglets is associated with a high rate of morbidity and mortality after birth due to gut dysfunction, and the underlying mechanisms remain poorly understood.
Tingting Fang, Gang Tian, Daiwen Chen, Jun He, Ping Zheng, Xiangbing Mao, Hui Yan, Bing Yu   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Potato R1 resistance gene confers resistance against Phytophthora infestans in transgenic tomato plants [PDF]

, 2010
Tomato is challenged by several pathogens which cause loss of production. One such pathogen is the oomycete Phytophthora infestans which is able to attack all the aerial parts of the plant.
Luigi Faino, ERCOLANO, MARIA RAFFAELLA, Testa, A., Maria Raffaella Ercolano, Paola Carli, Carli, P., Luigi Frusciante, FAINO, LUIGI, CRISTINZIO, GENNARO, Cristinzio, G., TESTA, ANTONINO, Gennaro Cristinzio, Ercolano, M.R., Antonino Testa, Faino, L., Frusciante, L., FRUSCIANTE, LUIGI, CARLI, PAOLA   +17 more
core   +1 more source

Unlocking the power of swine gut bacteria: newly isolated Blautia strain and its metabolites inhibit the replication of Salmonella Typhimurium in macrophages and alleviate DSS-induced colitis in mice

Journal of Animal Science and Biotechnology
Background Inflammatory bowel disease is a significant health concern for both humans and large-scale farm animals. In the quest for effective alternatives to antibiotics, next-generation probiotics (NGPs) have emerged as a promising option.
Jiatong Wei, Yang Liu, Hua Li, Ze Lu, Yanjiao Liu, Yifan Zhang, Cong Lan, Aimin Wu, Jun He, Jingyi Cai, Gang Tian, Daiwen Chen, Bing Yu, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Hui Yan, Jiayong Tang, Huifen Wang, Quyuan Wang, Yuheng Luo   +22 more
doaj   +1 more source

Rational consideration of Akkermansia muciniphila targeting intestinal health: advantages and challenges

npj Biofilms and Microbiomes, 2022
As one of the promising next-generation probiotics (NGPs), Akkermansia muciniphila, a well-known mucin-degrading bacterium, has been proven to be closely related to the metabolic diseases of its human host. However, the role of A. muciniphila in the host’
Yuheng Luo, Cong Lan, Hua Li, Qingyuan Ouyang, Fanli Kong, Aimin Wu, Zhihua Ren, Gang Tian, Jingyi Cai, Bing Yu, Jun He, André-Denis G. Wright   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling

Journal of Animal Science and Biotechnology, 2022
Background Consumption of resistant starch (RS) has been associated with various intestinal and systemic health benefits, but knowledge of its effects on intestinal health and inflammatory response in stressed birds is limited.
Simeng Qin, Weiqiang Bai, Todd J. Applegate, Keying Zhang, Gang Tian, Xuemei Ding, Shiping Bai, Jianping Wang, Li Lv, Huanwei Peng, Yue Xuan, Quifeng Zeng   +11 more
doaj   +1 more source