Results 171 to 180 of about 6,182,453 (264)

New functions of oxylipins released by pyroptotic cells

Acta Pharmaceutica Sinica B
Hui Xu, Hong-Li Tan, Hua-Jun Wang, Xiao-Fei Zheng, Yan-Ping Wu, Rong-Rong He   +5 more
doaj   +1 more source

Before hormones: early sex-specific mechanisms shaping nervous system development, function, and postnatal disease susceptibility. [PDF]

Front Behav Neurosci
Tsiarli MA, Larschan EN.
europepmc   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Allele frequency trajectories across age groups reveal ongoing natural selection shaping disease susceptibility. [PDF]

Am J Hum Genet
Chen JL, Kang ML, Lin CJ, Lo YH, Chen YJ, Lee HH, Tanapima V, Lin CK, Lee IH, Satta Y, Ko WY.   +10 more
europepmc   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Association of <i>SPHK1</i> polymorphisms with Alzheimer's disease susceptibility: Functional impact of the rs2247856 SNP on transcriptional efficiency. [PDF]

Alzheimers Dement (N Y)
Kim DJ, Kim YC, Jeong BH.
europepmc   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

Correction: Cerebrovascular phenotype analysis in <i>Gucy1a3</i> loss-of-function mice: insights into moyamoya disease susceptibility. [PDF]

Front Neurol
Wang P, Wang T, Yu J, Li J, Lin X, Zeng Y, Zhang X, Su S, Luo M.   +8 more
europepmc   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Antibiotic-induced gut microbiota dysbiosis and bile acid metabolism: implications for intestinal health, immune regulation, and disease susceptibility. [PDF]

Front Microbiol
AlRamadneh TN, Rizaev J, Hanumanthayya M, Al-Hussein MA, Mutee AF, Buriev M, Jumaniyazova N, Shefali.   +7 more
europepmc   +1 more source