Results 221 to 230 of about 828,302 (264)

Mendelian susceptibility to mycobacterial disease

Clinical Genetics, 2010
The host response to mycobacterial infection is mediated by the type I cytokine pathway (cell-mediated immunity). Deficiencies in this response result in susceptibility to poorly pathogenic mycobacterial species such as bacille Calmette-Guérin and environmental mycobacteria.
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Genetic Susceptibility in Infectious Diseases

Biotechnology and Genetic Engineering Reviews, 2000
The outcome of infectious disease varies tremendously between individuals due to a number of factors and may therefore be viewed by the geneticist as complex traits. The identification of genes which influence disease outcome is, at present, a resource-intensive project and therefore should not be undertaken without clear evidence, preferably from twin
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Genetic susceptibility to infectious diseases

Reproductive Toxicology, 2006
The clinical outcome of infectious disease (ID) is determined by a complex interaction between microorganism, host genetic factors and environment. Epidemiological studies have revealed differences within and between populations exposed to the same infectious agent, and in the prevalence or severity of the disease, underlying the relevance of the ...
CLEMENTI, MAURIZIO, DI GIANANTONIO E.
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Genetic susceptibility to Alzheimer disease

Trends in Genetics, 1995
Alzheimer disease (AD) is the leading cause of dementia in the elderly. Less than a decade ago, it was questioned as to whether or not genes were even involved in anything but rare early onset AD. Since that time, using a variety of genetic epidemiological and molecular biological techniques, four loci have been identified that play a role in the ...
M A, Pericak-Vance, J L, Haines
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Genetic susceptibility to Parkinson's disease

Neurology, 1991
Genetic factors clearly cause Lewy-body Parkinson's disease (PD) in a subset of autosomal-dominant families. However, most cases of PD are sporadic. The two most likely models of four discussed for sporadic PD are the reduced penetrance model and the multifactorial model.
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Human Susceptibility to Legionnaires’ Disease

2012
Legionella pneumophila is a facultative intracellular pathogen that is an important cause of pneumonia. Although host factors that may predispose to acquisition of Legionnaire's Disease (LD) include comorbid illnesses (e.g., diabetes, chronic lung disease), age, male sex, and smoking, many individuals have no identifiable risk factors.
William R, Berrington, Thomas R, Hawn
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Infectious disease: changing antibiotic susceptibility

Ophthalmology Clinics of North America, 2003
The field of ophthalmology is fortunate to have an array of antibiotics to treat bacterial infections. Because many of the older antibiotics are no longer useful for treating systemic infections, their use and associated acquired resistance have been reduced.
Regis P, Kowalski, Lisa M, Karenchak, Eric G, Romanowski   +2 more
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Cytokine genes and disease susceptibility

Cytokine, 2004
Complex networks of cytokines interact in a dynamic way to homeostatically regulate immune responses and other biological pathways. It is, therefore, not surprising that variation in cytokine level has been correlated with disease susceptibility and process.
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Particularities of Disease Susceptibility

Science's STKE, 2006
Some plants are susceptible to infection by certain bacteria, whereas others are not. The difference can lie in the presence or absence of a plant's defense against particular bacterial effector proteins. Studying Pseudomonas and Arabidopsis , Janjusevic et al. analyze
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Disease: virulence and susceptibility

2013
This chapter addresses elements in the pathogen that predispose to disease. These are collectively known as virulence factors. The chapter begins by displaying the two main categories of virulence factors: pathogen mechanisms directly or indirectly causing host damage, and pathogen mechanisms aimed at escaping host protective mechanisms, including ...
John H.L. Playfair, Gregory J. Bancroft
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