Results 91 to 100 of about 948,748 (269)

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Janus Photonic Graphics by Stratified Assembly of Two Distinct Colloids

Advanced Functional Materials, EarlyView.
Double‐sided Janus photonic micropatterns with vivid structural colors are fabricated through a single‐step bottom‐up strategy. Density‐driven stratification and depletion‐mediated crystallization of PMMA and PS binary colloids lead to exclusive lattices on opposite surfaces under centrifugal force.
Young Geon Kim, Yongseok Jung, Sehee Yang, Jiwoo Lee, Shin‐Hyun Kim   +4 more
wiley   +1 more source

Transparent and Robust LiCl–Organohydrogel Triboelectric Nanogenerator With Deep Learning Assisted Sensing

Advanced Functional Materials, EarlyView.
Develop a LiCl–PEI–PAM hydrogel with 3000% stretchability and excellent optical transparency. Through comparative studies of various salts, confirm that LiCl is the most suitable salt for high TENG output. Achieve excellent freeze‐resistant, dry‐resistant, and rapid self‐healing (10 s) properties even in extreme environments. Balance ionic conductivity,
Hai Anh Thi Le, Thien Trung Luu, Duc‐Manh Dinh, Kyehan Rhee, Kyungwho Choi, Dukhyun Choi, Yong Tae Park   +6 more
wiley   +1 more source

Modeling the coupled propagation of emotion, information, and disease considering emotional atmosphere in multi-layer networks

Frontiers in Physics
The interaction between information diffusion and emotional contagion exerts substantial influences on disease transmission. In this coupled process, both individual and collective emotional atmospheres play crucial roles by shaping the efficiency of ...
Liang’an Huo, Liang’an Huo, Yuanzhen Dai   +2 more
doaj   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Building Local Research Capacity for Global Pandemic Preparedness: Lessons from WHO Unity Studies and Their Expansion in India

Viruses
The rapid onset and progression of the COVID-19 pandemic highlighted the critical necessity for standardized, timely epidemiological investigations to generate actionable evidence for public health policy.
Yasir Alvi, Farzana Islam, Mohammad Ahmad, Richa Gautam, Aqsa Shaikh, Musharraf Husain, Kartikey Yadav, Mohammad Rashid, Shyambhavee Behera, Nicki L. Boddington, Ashok Basnet, Pushpa Ranjan Wijesinghe   +11 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Norovirus Outbreak Due to Person-to-person Transmission in a College in Kerala, India, 2021

Indian Journal of Public Health
We investigated a cluster of acute gastroenteritis reported from a college in Kerala on December 1, 2021. We defined a suspect case as an occurrence of vomiting or at least three episodes of loose stools within 24 h.
Salin K. Eliyas, Lakshmi Geetha Gopalakrishnan, Srinath Ramamurthy, Manikandanesan Sakthivel, Uma Maheshwari Thankachi Sankaran, Kavya Karunakaran, Mohankumar Raju   +6 more
doaj   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source