Results 71 to 80 of about 7,199,284 (318)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Reducing Plasmodium falciparum malaria transmission in Africa: a model-based evaluation of intervention strategies. [PDF]

, 2010
BACKGROUND: Over the past decade malaria intervention coverage has been scaled up across Africa. However, it remains unclear what overall reduction in transmission is achievable using currently available tools.
Bousema, Teun, Ghani, Azra C, Chris J. Drakeley, Lucy C. Okell, White Michael, Hinsley, Wes, Hinsley, W, Azra C Ghani, Ghani, AC, María-Gloria Basáñez, Griffin, JT, Wes Hinsley, White, Michael, Jamie T. Griffin, Okell Lucy C., Ghani, Azra C., T. Deirdre Hollingsworth, Griffin, Jamie T, Bousema Teun, Jamie T Griffin, Churcher Thomas S., Basáñez, MG, Hollingsworth, T Deirdre, Michael White, Ghani Azra C., Ferguson, Neil M., Chris J Drakeley, Drakeley, Chris J, T Deirdre Hollingsworth, Griffin, Jamie T., Lucy C Okell, Hollingsworth T. Deirdre, Drakeley, CJ, Hollingsworth, TD, Hollingsworth, T. Déirdre, Okell, Lucy C, Churcher, Thomas S, Basáñez María-Gloria, Griffin Jamie T., Teun Bousema, Azra C. Ghani, Thomas S Churcher, Ferguson, Neil M, Basáñez, María-Gloria, Ferguson Neil M., Thomas S. Churcher, Bousema, T, Churcher, TS, Ferguson, NM, Drakeley, Chris J., Hinsley Wes, Churcher, Thomas S., Neil M Ferguson, Drakeley Chris J., Okell, LC, Neil M. Ferguson, Okell, Lucy C., White, M   +57 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Sheep Movement Networks and the Transmission of Infectious Diseases [PDF]

, 2010
Background and Methodology: Various approaches have been used to investigate how properties of farm contact networks impact on the transmission of infectious diseases.
Nicholas J. Savill, Nicholas J Savill, Woolhouse Mark E. J., Mark E J Woolhouse, Volkova Victoriya V., Savill, Nicholas J., Howey Richard, Savill Nicholas J., Mark E. J. Woolhouse, Howey, Richard, Victoriya V Volkova, Victoriya V. Volkova, Volkova, Victoriya V., Richard Howey, Woolhouse, Mark E. J.; id_orcid   +14 more
core   +2 more sources

Maternal Transmission of Alzheimer Disease [PDF]

Alzheimer Disease & Associated Disorders, 2012
Some researchers propose maternal Alzheimer disease (AD) inheritance. We compared dementia family histories in AD cases and cognitively normal controls. We expected more mothers to have AD in both groups. If maternal risk was not only due to female longevity, more AD cases' than controls' mothers should have dementia.
Kristin A, Heggeli, Julia, Crook, Colleen, Thomas, Neill, Graff-Radford   +3 more
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Modelling knowlesi malaria transmission in humans: Vector preference and host competence [PDF]

, 2010
Background: Plasmodium knowlesi, a malaria species that normally infects long-tailed macaques, was recently found to be prevalent in humans in Southeast Asia.
Michael B Bonsall, Bonsall, Michael, Yan, G, Yakob, L, Guiyun Yan, Bonsall, Michael B., Yan, Guiyun, Yakob Laith, Bonsall, MB, Bonsall Michael B, Laith Yakob, Yan Guiyun, Yakob, Laith, Bonsall, Michael B   +13 more
core   +1 more source

Understanding pathogen transmission dynamics in waterbird communities: At what scale should interactions be studied?

South African Journal of Science, 2011
Pathogen transmission in animal populations is contingent on interactions between and within species. Often standard ornithological data (e.g. total counts at a wetland) are the only data available for assessing the risks of avian pathogen transmission ...
Lindy MacGregor, Graeme Cumming, Philip Hockey   +2 more
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source