Results 31 to 40 of about 348,589 (256)

Assembly and functional analysis of an S/MAR based episome with the cystic fibrosis transmembrane conductance regulator gene [PDF]

open access: yes, 2018
Improving the efficacy of gene therapy vectors is still an important goal toward the development of safe and efficient gene therapy treatments. S/MAR (scaffold/matrix attached region)-based vectors are maintained extra-chromosomally in numerous cell ...
Ascenzioni, Fiorentina   +10 more
core   +3 more sources

Morphological and Molecular Techniques as an Integrative Approach to Identifying Sandfly (Diptera: Psychodidae) Vectors of Leishmaniasis in the Jazan and Asir Regions, Southwestern Saudi Arabia

open access: yesInternational Journal of Zoology
Sandflies are the primary vectors of leishmaniasis, a parasitic disease of major public health concern in Saudi Arabia. While morphological identification remains the standard for species classification in the Jazan and Asir regions, distinguishing ...
Elsiddig Noureldin   +15 more
doaj   +1 more source

Vector-borne diseases in pregnancy [PDF]

open access: yesTherapeutic Advances in Infectious Disease, 2020
Vector-borne infections cause a significant proportion of world-wide morbidity and mortality and many are increasing in incidence. This is due to a combination of factors, primarily environmental change, encroachment of human habitats from urban to peri-urban areas and rural to previously uninhabited areas, persistence of poverty, malnutrition and ...
Brendan O’Kelly, John S. Lambert
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Population genetic structure analysis of Anopheles kleini in the Republic of Korea based on the mitochondrial COI gene

open access: yesMalaria Journal
Background Anopheles kleini is a competent vector mainly observed in the northern, malaria-risk areas of the Republic of Korea (ROK). In this study, the population genetic structure of An.
Haneul Jung   +4 more
doaj   +1 more source

Identification of Hard Ticks (Acari: Ixodidae) in Southern Villages of Ahvaz to Khorramshahr Road in Southwest Iran, 2021 [PDF]

open access: yesArmaghane Danesh Bimonthly Journal, 2023
Background & aim: Ticks, as external parasites, biological carriers and reservoirs of various diseases, play a role in the transmission of various disease agents to humans and animals.
V Ansari   +8 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Geographic distribution of Orientia tsutsugamushi strains on chigger mites in the Republic of Korea (2021–2023)

open access: yesParasites & Vectors
Background Scrub typhus is caused by the larvae of chigger mites infected with Orientia tsutsugamushi, and many cases are reported globally. The virulence and prevalence of O. tsutsugamushi varies depending on the strain and region.
Hyeon Seung Lee   +3 more
doaj   +1 more source

Low sensitivity of ParaHIT-f rapid malaria test among patients with fever in rural health centers, Northern Tanzania

open access: yesJournal of Infection in Developing Countries, 2011
Introduction: Several rapid diagnostic tools for malaria are currently available in local markets. However, diagnostic accuracy varies widely. The present study was conducted to evaluate a cheaply and easily available rapid diagnostic malaria test ...
Eliningaya John Kweka   +7 more
doaj   +1 more source

Kudoa septempunctata Spores Cause Acute Gastroenteric Symptoms in Mouse and Musk Shrew Models as Evidenced In Vitro in Human Colon Cells

open access: yesPathogens, 2023
Kudoa septempunctata is a myxosporean parasite that infects the trunk muscles of olive flounder (Paralichthys olivaceus) and has been reported to cause foodborne illnesses in humans. However, the molecular mechanisms underlying K.
Sung-Hee Hong   +5 more
doaj   +1 more source

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