Results 41 to 50 of about 382,062 (313)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Geographic distribution of Orientia tsutsugamushi strains on chigger mites in the Republic of Korea (2021–2023)

open access: yesParasites & Vectors
Background Scrub typhus is caused by the larvae of chigger mites infected with Orientia tsutsugamushi, and many cases are reported globally. The virulence and prevalence of O. tsutsugamushi varies depending on the strain and region.
Hyeon Seung Lee   +3 more
doaj   +1 more source

Research needs for Chagas disease prevention.

open access: yes, 2010
We present an overview of the two main strategies for the primary (vector control) and secondary (patient care) prevention of Chagas disease (CD). We identify major advances, knowledge gaps, and key research needs in both areas.
Santos, Walter S   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Evaluation of vector competence of Culex tritaeniorhynchus and Culex pipiens pallens for Japanese encephalitis virus genotype III and V

open access: yesParasites & Vectors
Background Japanese encephalitis virus (JEV) is a major mosquito-borne pathogen, primarily transmitted by Culex tritaeniorhynchus in rural regions. In the Republic of Korea (ROK), genotype V (GV) has become the dominant JEV strain since 2010, raising ...
Ji-Young Kwon   +3 more
doaj   +1 more source

Identification of Hard Ticks (Acari: Ixodidae) in Southern Villages of Ahvaz to Khorramshahr Road in Southwest Iran, 2021 [PDF]

open access: yesArmaghane Danesh Bimonthly Journal, 2023
Background & aim: Ticks, as external parasites, biological carriers and reservoirs of various diseases, play a role in the transmission of various disease agents to humans and animals.
V Ansari   +8 more
doaj  

A set of ontologies to drive tools for the control of vector-borne diseases

open access: yes, 2009
We are developing a set of ontologies that deal with vector-borne diseases and the arthropod vectors that transmit them. For practical reasons (application priorities), we initiated this project with an ontology of insecticide resistance followed by a ...
Christos Louis   +5 more
core   +1 more source

Containment of Arthropod Disease Vectors [PDF]

open access: yesILAR Journal, 2005
Effective containment of arthropod vectors of infectious diseases is necessary to prevent transmission of pathogens by released, infected vectors and to prevent vectors that escape from establishing populations that subsequently contribute to increased disease.
openaire   +2 more sources

Transcriptomics and disease vector control [PDF]

open access: yesBMC Biology, 2010
Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.
Ranson Hilary, Vontas John, Alphey Luke
openaire   +4 more sources

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