Results 51 to 60 of about 383,949 (313)
Containment of Arthropod Disease Vectors [PDF]
Effective containment of arthropod vectors of infectious diseases is necessary to prevent transmission of pathogens by released, infected vectors and to prevent vectors that escape from establishing populations that subsequently contribute to increased disease.
openaire +2 more sources
Transcriptomics and disease vector control [PDF]
Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.
Ranson Hilary, Vontas John, Alphey Luke
openaire +4 more sources
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Self-inactivating gammaretroviral vectors for the gene therapy of chronic granulomatous disease [PDF]
Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency characterized by defective intracellular oxidative killing of ingested invading microbes by PMN and monocytes.
Moreno Carranza, Bibiana
core
Identification of Hard Ticks (Acari: Ixodidae) in Southern Villages of Ahvaz to Khorramshahr Road in Southwest Iran, 2021 [PDF]
Background & aim: Ticks, as external parasites, biological carriers and reservoirs of various diseases, play a role in the transmission of various disease agents to humans and animals.
V Ansari +8 more
doaj
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Microscale characterisation of a manufacturing route for lentiviral vectors [PDF]
Lentiviral vectors used in clinical trials are currently produced by transient transfection of adherent human embryonic kidney (HEK)293(T) cells. However, this approach is not scalable and for commercialisation the development of alternative strategies ...
Guy, HM
core
Introduction: Aedes aegypti, and Culex pipiens are the primary vector of human arboviral diseases, which represent an important public health problem.
Alireza Sanei-Dehkordi +7 more
doaj +1 more source
Background: In Iran, the prospect of malaria control relies mainly on insecticides used against the genus Anopheles (Diptera: Culicidae) as important vectors of malaria, arboviruses, and so on.
Ebrahim Abbasi +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

