Results 61 to 70 of about 382,062 (313)

Kudoa septempunctata Spores Cause Acute Gastroenteric Symptoms in Mouse and Musk Shrew Models as Evidenced In Vitro in Human Colon Cells

Pathogens, 2023
Kudoa septempunctata is a myxosporean parasite that infects the trunk muscles of olive flounder (Paralichthys olivaceus) and has been reported to cause foodborne illnesses in humans. However, the molecular mechanisms underlying K.
Sung-Hee Hong, Ji-Young Kwon, Soon-Ok Lee, Hee-Il Lee, Sung-Jong Hong, Jung-Won Ju   +5 more
doaj   +1 more source

A crossover study to evaluate the diversion of malaria vectors in a community with incomplete coverage of spatial repellents in the Kilombero Valley, Tanzania [PDF]

, 2016
Malaria elimination is unlikely to occur if vector control efforts focus entirely on transmission occurring indoors without addressing vectors that bite outdoors and outside sleeping hours.
Lobo, Neil F, Kreppel, Katharina, Mayagaya, Valeriana, Ross, Amanda, Lobo, Neil F., Maia, Marta Ferreira, Roman, Deogratius, Mbeyela, Edgar, Moore, Sarah Jane   +8 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Prevalence of head lice infestation and its associated factors in primary school students in Shiraz City, Fars Province, Iran

BMC Public Health
Background Pediculus humanus capitis is an obligate ectoparasite transmitted mainly through direct head-to-head contact, affecting millions of school-aged children worldwide.
Saeed Shahabi, Mitra Boroomand, Abbas Paksa, Zahra Nasiri, Zahra Vahabi-Baabsangi, Mozaffar Vahedi, Zahra Rousta, Shahin Saeedi, Azim Paksa   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Linking remote sensing, land cover and disease [PDF]

, 2000
Land cover is a critical variable in epidemiology and can be characterized remotely. A framework is used to describe both the links between land cover and radiation recorded in a remotely sensed image, and the links between land cover and the disease ...
Milton, E. J., Curran, Paul J., Milton, E.J., P.J. Curran, Foody, G.M., Curran, P.J., Foody, Giles M., Atkinson, Peter M., E.J. Milton, Atkinson, P.M., P.M. Atkinson, G.M. Foody   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The relationships between microbiome diversity and epidemiology in domestic species of malaria-mediated mosquitoes of Korea

Scientific Reports, 2023
Microbiota in the mosquito plays an important role in their behavior and vector competence. The composition of their microbiome is strongly influenced by the environment, especially their habitat.
Jeong Hyeon Lee, Hyun-Woo Kim, Bilal Mustafa, Hee Il Lee, Hyung Wook Kwon   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Leishmania major Infection in Synanthropic Rodents: Evidence for the Urbanization of Zoonotic Cutaneous Leishmaniasis (ZCL) in Southern Iran

Canadian Journal of Infectious Diseases and Medical Microbiology
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to investigate the infection of rodents with Leishmania major in an urban area of Fars Province, located in southern Iran.
Saeed Shahabi, Kourosh Azizi, Qasem Asgari, Bahador Sarkari   +3 more
doaj   +1 more source