Results 71 to 80 of about 348,589 (256)

Integrating vector control across diseases [PDF]

BMC Medicine, 2015
Vector-borne diseases cause a significant proportion of the overall burden of disease across the globe, accounting for over 10 % of the burden of infectious diseases. Despite the availability of effective interventions for many of these diseases, a lack of resources prevents their effective control.
Golding, N, Wilson, AL, Moyes, CL, Cano, J, Pigott, DM, Velayudhan, R, Brooker, SJ, Smith, DL, Hay, SI, Lindsay, SW   +9 more
openaire   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]

, 2018
Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R., Montgomery, Susan P., Perez-Zetune, Victoria, Stillwaggon, Eileen   +3 more
core   +2 more sources

Transcriptomics and disease vector control [PDF]

BMC Biology, 2010
Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.
Ranson Hilary, Vontas John, Alphey Luke
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Scorpion species distribution and sting epidemiology in Dena and Boyer-Ahmad, Iran – Implications for management

Parasite Epidemiology and Control
Scorpion envenomation represents a significant public health burden in Iran, particularly in Kohgiluyeh and Boyer-Ahmad Province, which reports 40,000 to 50,000 cases annually.
Mohsen Fakhraei, Raziyeh Shahheidari, Amir Hossein Roozitalab, Kourosh Azizi, Mohsen Kalantari   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

First report on the molecular phylogenetics and population genetics of Aedes aegypti in Iran

Parasites & Vectors
Background Aedes aegypti, the primary vector of various human arboviral diseases, is a significant public health threat. Aedes aegypti was detected in Iran in 2018, in Hormozgan province, but comprehensive information regarding its genetic diversity and ...
Azim Paksa, Kourosh Azizi, Saideh Yousefi, Sorna Dabaghmanesh, Saeed Shahabi, Alireza Sanei-Dehkordi   +5 more
doaj   +1 more source

West Nile virus transmission. results from the integrated surveillance system in Italy, 2008 to 2015 [PDF]

, 2016
IIn Italy a national Plan for the surveillance of imported and autochthonous human vector-borne diseases (chikungunya, dengue, Zika virus disease and West Nile virus (WNV) disease) that integrates human and veterinary (animals and vectors) surveillance ...
Angelini, P., Baldanti, Fausto, Bedeschi, Emanuela, Bella, A., Bellini, R., Benedetti, Eleonora, Boccolini, Daniela, Busani, Luca, Cagarelli, R., Calistri, P., Cenci, Corrado, Chiari, M., Costa, Nanni, Declich, Silvia, di Luca, Marco, Dottori, Michele, Faccin, Francesca, Farioli, Marco, Fiorentini, Cristiano, Fortuna, Claudia, Gismondo, Mariarita, Gramegna, Maria, Gualanduzzi, Claudio, Landini, Maria Paola, Lavazza, A., Lelli, Davide, Liumbruno, Giancarlo Maria, Lombardini, Annalisa, Lombardini, L., Maraglino, Francesco, Mattivi, Andrea, Monaco, F., Napoli, Christian, Natalini, Silvano, Palú, G., Parodi, Patrizia, Pezzotti, Patrizio, Piatti, A., Prosperi, Alice, Pupella, S., Remoli, Maria Elena, Rezza, Gianni, Rizzo, Caterina, Romi, Roberto, Rossi, Davide, Rovida, Francesca, Russo, F., Severini, Francesco, Squintani, Gabriele, Tamba, M., Toma, Luciano, Venturi, G., Zanchetta, Nadia, Zanella, Francesca   +53 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source