Results 121 to 130 of about 22,218,716 (335)

Magnesium (Mg2+) Deficiency, Not Well-Recognized Non-Infectious Pandemic: Origin and Consequence of Chronic Inflammatory and Oxidative Stress-Associated Diseases [PDF]

, 2022
Yalith Lyzet Arancibia‐Hernández, Estefani Yaquelin Hernández‐Cruz, José Pedraza-Chaverrı́   +2 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

MicroRNA-346 Mediates Tumor Necrosis Factor α–Induced Downregulation of Gut Epithelial Vitamin D Receptor in Inflammatory Bowel Diseases [PDF]

, 2014
Yunzi Chen, Jie Du, Zhongyi Zhang, Tianjing Liu, Yongyan Shi, Xin Ge, Yan Chun Li   +6 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Diagnosis of some diseases through biomarkers [PDF]

, 2019
Muchos gatos, como los perros, sufren de diferentes enfermedades. que en ese momento no permiten mostrar síntomas o signos que permiten identificar que la mascota sufre una enfermedad grave, ya que las características de los gatos son diferentes a las de
Gutiérrez Rodríguez, Andrea
core  

Safety analysis in patients with autoimmune disease receiving allogeneic mesenchymal stem cells infusion: a long-term retrospective study [PDF]

, 2018
Jun Liang, Huayong Zhang, Wei Kong, Wei Deng, Dandan Wang, Xuebing Feng, Cheng Zhao, Bingzhu Hua, Hong Wang, Lingyun Sun   +9 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Unraveling diarrheal disease knowledge, understanding, and management practices among climate change vulnerable coastal communities in Ghana

Frontiers in Public Health
IntroductionDiarrheal disease is a global public health concern, particularly in low-income countries. In Ghana, widespread issues like inadequate sanitation, unsafe drinking water, malnutrition, and poor hygiene practices contribute to the high ...
Yaw Agyeman Boafo, Fidelia N. A. Ohemeng, Jesse Ayivor, Joseph Armah Ayitiah, Dzidzo Yirenya-Tawiah, Adelina Mensah, Cecilia Datsa, Ted Yemoh Annang, Lois Adom   +8 more
doaj   +1 more source

When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases [PDF]

, 2011
Vincent Navratil, Benoı̂t de Chassey, Chantal Combe, Vincent Lotteau   +3 more
openalex   +1 more source