Results 121 to 130 of about 12,576,478 (338)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
HemaSphere, 2015 Bone disease is one of the most common complications of multiple myeloma. It is the result of increased osteoclast activity which is not compensated by osteoblast activity and leads to osteolytic lesions characterized by bone pain and increased risk for pathological fracture, spinal cord compression and need for radiotherapy or surgery to the bone ...
openaire +4 more sources
Network perspective of histamine related diseases [PDF]
, 2017 Histamine is the most pleiotropic biogenic amine. Produced and stored by a limited set of cells—histaminergic neurons, enterochromaffin-like cells, and mast cells—it broadcasts intercellular communication signals to a wide variety of cell types through ...
Medina, Miguel Ángel +3 more
core
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2015 Purpose: determination of anthropometrical and somatic indicators and factors of school anxiety of 11-12 yrs age boys - members of special health groups at urban and countryside schools.
G.V. Tamozhanskaya
doaj
IJAIN (International Journal of Advances in Intelligent Informatics)The early treatment and detection of plant diseases are important processes, as many diseases affecting crops are highly contagious. Recent advancements in deep learning have helped to provide innovative tools that have not only assisted early detection,
Nabila Mansouri +2 more
doaj +1 more source
An Inquiry into the Nature of Frequency Distributions Representative of Multiple Happenings with Particular Reference to the Occurrence of Multiple Attacks of Disease or of Repeated Accidents [PDF]
, 1920 Major Greenwood, George Yule
openalex +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Further observations on the relative size and form of the right and left testes of pigeons in health and disease and as influenced by hybridity [PDF]
, 1918 Oscar Riddle
openalex +1 more source