Results 121 to 130 of about 10,435,514 (291)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2015 Purpose: determination of anthropometrical and somatic indicators and factors of school anxiety of 11-12 yrs age boys - members of special health groups at urban and countryside schools.
G.V. Tamozhanskaya
doaj
Frontiers in Veterinary ScienceIntroductionGastrointestinal (GI) disorders and renal dysfunction are common and clinically significant conditions in dromedary camels (Camelus dromedarius). However, their interrelationship—representing the gut–renal axis—remains poorly understood. This
Mohamed Tharwat +3 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Cryomicroneedle Arrays for Biotherapeutics Delivery
Small ScienceBiotherapy offers a promising approach for treating a variety of diseases. However, the lack of advanced delivery systems remains a significant barrier to improve the efficacy, safety, and cost‐effectiveness of biotherapeutics.
Chunli Yang +9 more
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AgricultureThis study investigated the effects of different water management practices on the growth, yield, and grain quality of rice grown under environmentally friendly farming methods in Apgok-Ri, Gungnyu-Myeon, Uiryeong-Gun, from 2022 to 2024.
SeungKa Oh, Young-Son Cho
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
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Metabolic regulation of regulatory T cells: mechanisms, heterogeneity, and implications in disease
Frontiers in ImmunologyRegulatory T (Treg) cells are essential for maintaining immune tolerance, preventing autoimmune responses, and supporting tissue repair. Tregs employ a flexible and diverse metabolic program that includes glycolysis, oxidative phosphorylation (OXPHOS ...
Feven Getachew +7 more
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