Living donor liver transplantation for autoimmune hepatitis in identical monozygotic twins: a case report [PDF]
Clinical Transplantation and ResearchLiver transplantation (LT) is an effective treatment for end-stage liver diseases, including autoimmune hepatitis. Advances in immunosuppressive therapy have improved patient and graft survival; however, these treatments can cause serious side effects ...
Kulbhushan Haldeniya +7 more
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Digital Twins in Healthcare and Their Applicability in Rhinology: A Narrative Review [PDF]
Journal of Rhinology, 2023 Digital twins were initially introduced in the aerospace industry, but they have been applied to the medical field in the 2020s. The development of the Internet of Things, sensor technology, cloud computing, big data analysis, and simulation technology ...
Minhae Park, Namkee Oh, Yong Gi Jung
doaj +1 more source
Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis [PDF]
, 2013 The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis.
A Darfeuille-Michaud +49 more
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A Novel Homozygous Mutation of Classic Bartter Syndrome Presenting with Renal Cysts in 6-year-Old Identical Twin Boys : A Case Report [PDF]
Childhood Kidney Diseases, 2021 Bartter syndrome is an autosomal recessive hypokalemic salt-losing tubulopathy, and classic Bartter syndrome is associated with mutations in the CLCNKB gene.
Min Hwa Son, Hyung Eun Yim, Kee Hwan Yoo
doaj +1 more source
Journal of Reconstructive Microsurgery Open, 2023 Background Composite tissue allotransplants are performed for various defects when local, or distant reconstructive options are limited. Though this type of transplant replaces similar tissue, it is complicated by immunosuppression.
Cemile Nurdan Ozturk +4 more
doaj +1 more source
Differences in individual life path choices affecting life expectancy and health in Russia [PDF]
E3S Web of Conferences, 2020 In this study we examined 100 pairs of monozygotic (MZ) twins to determine if lifestyle differences between control and experimental twins affected lifespan and health. We used the twin database of the Russian Humanitarian Scientific Foundation.
Berezina Tatiana
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DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes. [PDF]
PLoS Genetics, 2012 Monozygotic (MZ) twins do not show complete concordance for many complex diseases; for example, discordance rates for autoimmune diseases are 20%-80%. MZ discordance indicates a role for epigenetic or environmental factors in disease.
Kristina Gervin +9 more
doaj +1 more source
Familial aggregation of multimorbidity in Sweden: national explorative family study
BMJ Medicine, 2023 Objectives To examine whether multimorbidity aggregates in families in Sweden.Design National explorative family study.Setting Swedish Multigeneration Register linked to the National Patient Register, 1997-2015.
Anders Halling +5 more
doaj +1 more source
Metagenomic Analysis of the Structure and Function of the Human Gut Microbiota in Crohn's Disease [PDF]
, 2010 Inflammatory bowel diseases (IBD), such as Crohn’s disease, are chronic, immunologically mediated disorders that have severe medical consequences.
Claire M. Fraser-Liggett
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Ageing And Cancer As Diseases Of Epigenesis [PDF]
, 2009 Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
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