Results 11 to 20 of about 47,212 (310)

Digital twins for chronic lung diseases

European Respiratory Review
Digital twins have recently emerged in healthcare. They combine advances in cyber–physical systems, modelling and computation techniques, and enable a bidirectional flow of information between the physical and virtual entities.
Apolline Gonsard, Martin Genet, David Drummond   +2 more
doaj   +2 more sources

Pili torti and multiple facial milia as an expression of ectodermal dysplasia in monozygotic twins

Przegląd Dermatologiczny, 2014
Introduction . Genodermatoses – congenital diseases with diverse clinical presentation – are caused by ectodermal defects. pili torti and milia may be features of these defects. Concomitantly these symptoms are present in rare genodermatoses: Bazex-Dupre-
Monika Sikorska, Aneta Szczerkowska-Dobosz, Dorota Purzycka-Bohdan, Roman Nowicki   +3 more
doaj   +2 more sources

Epigenetic Basis of Twin Discordance in Diseases: Future Benefits

Gynecology Obstetrics & Reproductive Medicine, 2018
Monozygotic twins share the same genotype since they are derived from the same zygote. However, monozygotic (MZ) twin siblings frequently present many phenotypic differences, such as their susceptibilities to diseases.
Ayse Banu Demir, Namik Demir
doaj   +2 more sources

A Twin Study of Perthes Disease [PDF]

Pediatrics, 2016
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an idiopathic avascular necrosis of the femoral head. Its etiology is poorly understood, although previous studies have implicated low birth weight and possible genetic determinants. The aim of this study was to identify potential birth weight and genetic associations
Metcalfe, David, Van Dijck, Stephanie, Parsons, Nicolas, Christensen, Kaare, Perry, Daniel C   +4 more
openaire   +2 more sources

A study of diabetes mellitus within a large sample of Australian twins. [PDF]

, 2008
Udgivelsesdato: 2008-FebTwin studies of diabetes mellitus can help elucidate genetic and environmental factors in etiology and can provide valuable biological samples for testing functional hypotheses, for example using expression and methylation studies
Kyvik, Kirsten O; id_orcid, Condon, Julianne, Luciano, Michelle, Kyvik, Kirsten O, Duffy, David L, Shaw, Joanne E, Martin, Nicholas G   +6 more
core   +1 more source

Transcriptome Profiling Reveals Differential Expression of Circadian Behavior Genes in Peripheral Blood of Monozygotic Twins Discordant for Parkinson’s Disease

Cells, 2022
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Investigating individuals with the most identical genetic background is optimal for minimizing the genetic contribution to gene expression.
Ekaterina I. Semenova, Ivan N. Vlasov, Suzanna A. Partevian, Anna V. Rosinskaya, Ivan N. Rybolovlev, Petr A. Slominsky, Maria I. Shadrina, Anelya Kh. Alieva   +7 more
doaj   +1 more source

A Twin Study of Early-Childhood Asthma in Puerto Ricans [PDF]

, 2013
Background:The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood.Objective:To examine the relative contributions of genetics and environment to early-childhood ...
Canino Glorisa, Judy L. Silberg (430008), Gillespie, Nathan A., Lange, Nancy E, Lasky-Su, J, Nathan A Gillespie, Supinda Bunyavanich, Canino, G, Nancy E. Lange (430010), Silberg, JL, Juan C. Celedόn (430011), Lange Nancy E., Glorisa Canino, Glorisa Canino (151346), Bunyavanich, S, Celedόn Juan C., Celedόn, Juan C, Gillespie, NA, Gillespie, Nathan A, Gillespie Nathan A., Celedn, JC, Jessica Lasky-Su, Lasky-Su Jessica, Celedόn, Juan C., Nancy E Lange, Judy L Silberg, Bunyavanich, Supinda, Bunyavanich Supinda, Lange, Nancy E., Silberg, Judy L., Silberg, Judy L, Celedon, Juan C., Juan C Celedón, Nathan A. Gillespie (430009), Lange, NE, Lasky-Su, Jessica, Jessica Lasky-Su (273842), Supinda Bunyavanich (430007), Canino, Glorisa, Silberg Judy L.   +39 more
core   +1 more source

Alzheimer's disease in twins

Biomedicine & Pharmacotherapy, 1997
Besides familial Alzheimer's disease (AD), the genetic susceptibility has also been found in sporadic cases of AD, mostly related to the apolipoprotein E polymorphism. The penetrance of AD is determined by age and probably by environmental exposure. Gene-environment interaction of a disease can be examined through studies of twins.
I, Räihä, J, Kaprio, M, Koskenvuo, T, Rajala, L, Sourander   +4 more
openaire   +2 more sources

Kawasaki Disease in Monozygotic Twins [PDF]

Pediatric Infectious Disease Journal, 2011
Multiple lines of evidence suggest that susceptibility to Kawasaki disease (KD) is influenced by host genetics. Subclinical coronary artery vasculitis may be present in monozygotic twins who are discordant for clinical signs of KD. Health care providers should consider laboratory testing and echocardiography in both monozygotic twins when only one twin
Aubri, Kottek, Chisato, Shimizu, Jane C, Burns   +2 more
openaire   +2 more sources

Implante coclear na síndrome Kearns-Sayre: estudo de caso de irmãs gêmeas

Audiology: Communication Research, 2017
RESUMO A deficiência auditiva pode estar relacionada com diversos fatores, entre eles, a perda auditiva decorrente de determinadas síndromes genéticas.
Letícia Sampaio de Oliveira, Karina Costa Brosco, Eduardo Boaventura Oliveira, Kátia de Freitas Alvarenga   +3 more
doaj   +1 more source