Results 51 to 60 of about 157,074 (374)

Comparative study of dermatoglyphic patterns in identical twins

National Journal of Clinical Anatomy, 2017
Background and aims: Dermatoglyphics has been studied extensively in chromosomal disorders and also in various diseases. Identical twins cannot be distinguished based on DNA.
R Anita Gune, Satish Patki, J Anand Pote
doaj   +1 more source

Hyperbaric oxygen therapy of angiopathic changes in patients with inherited gene imbalance [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2007
Introduction Phenotype match inherited by genes is in most cases present in monozygotic twins. Their phenotypic resemblance is unfortunately characterized by strong susceptibility for the development of chronic non-infectious diseases.
Brkić Predrag, Mitrović Ana, Rakić Miodrag, Grajić Mirko, Jovanović Tomislav   +4 more
doaj   +1 more source

Kawasaki Disease in Monozygotic Twins [PDF]

Pediatric Infectious Disease Journal, 2011
Multiple lines of evidence suggest that susceptibility to Kawasaki disease (KD) is influenced by host genetics. Subclinical coronary artery vasculitis may be present in monozygotic twins who are discordant for clinical signs of KD. Health care providers should consider laboratory testing and echocardiography in both monozygotic twins when only one twin
Jane C. Burns, Aubri Kottek, Chisato Shimizu   +2 more
openaire   +3 more sources

Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders

Population Ecology, EarlyView.
We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa, Andrea Costa, Sebastiano Salvidio   +2 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome. [PDF]

, 2019
BackgroundAngelman syndrome (AS) is a neurodevelopmental disorder that is caused by maternal genetic deficiency of a gene that encodes E6-AP ubiquitin-protein ligase (gene symbol UBE3A) mapping to chromosome 15q11-q13.
Anselm, Irina, Bacino, Carlos A, Bichell, Terry Jo, Bird, Lynne M, Golden, Stephanie, Han, Julia, Kimonis, Virginia, Peters, Sarika U, Waisbren, Susan   +8 more
core  

Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia

Clinical and Translational Medicine, 2017
Background Monozygotic twins are valuable in assessing the genetic vs environmental contribution to diseases. In the era of complete genome sequences, they allow identification of mutational mechanisms and specific genes and pathways that offer ...
C. A. Castellani, M. G. Melka, J. L. Gui, A. J. Gallo, R. L. O’Reilly, S. M. Singh   +5 more
doaj   +1 more source

Using the Non-Adoption, Abandonment, Scale-Up, Spread, and Sustainability (NASSS) Framework to Identify Barriers and Facilitators for the Implementation of Digital Twins in Cardiovascular Medicine

Sensors, 2023
A digital twin is a computer-based “virtual” representation of a complex system, updated using data from the “real” twin. Digital twins are established in product manufacturing, aviation, and infrastructure and are attracting significant attention in ...
Peter D. Winter, Timothy J. A. Chico
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Envisioning the Future of Personalized Medicine: Role and Realities of Digital Twins

Journal of Medical Internet Research
Digital twins have emerged as a groundbreaking concept in personalized medicine, offering immense potential to transform health care delivery and improve patient outcomes.
Alexandre Vallée
doaj   +1 more source