Results 71 to 80 of about 47,212 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Influence of chorionicity on the heritability estimates of blood pressure: a study in twins

, 2003
Influence of chorionicity on the heritability estimates of blood pressure: a study in twins. Fagard RH, Loos RJ, Beunen G, Derom C, Vlietinck R. Hypertension and Cardiovascular Rehabilitation Unit, Faculty of Medicine, University of Leuven, KU Leuven ...
Beunen, G., Vlietinck, R.F.M., Fagard, R.H., Derom, C., Loos, R.J.   +4 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Determinants of birthweight and intrauterine growth in liveborn twins

, 2005
We explored the relationship of umbilical cord insertion and fusion of placentas with birthweight in monozygotic monochorionic (MZ MC), monozygotic dichorionic (MZ DC), and dizygotic (DZ) twins.
Ruth J. F. Loos, Catherine Derom, Vlietinck, R.F.M., Derom, R., Robert Vlietinck, Derom, C., Loos, R.J., Robert Derom   +7 more
core   +1 more source

Dietary intake and rural-urban migration in India: a cross-sectional study. [PDF]

, 2011
BACKGROUND: Migration from rural areas of India contributes to urbanisation and lifestyle change, and dietary changes may increase the risk of obesity and chronic diseases.
K Srinath Reddy, Ness, Andy, Andy Ness, Reddy, K Srinath, Liza Bowen, Ebrahim, S, Kinra, S, Bharathi, AV, A V Bharathi, Bianca De Stavola, Reddy, KS, A.V. Bharathi, Bowen, Liza, Prabhakaran, B, Prabhakaran, Dorairaj, Sanjay Kinra, Shah Ebrahim, De Stavola, B, De Stavola, Bianca, Kinra, Sanjay, K. Srinath Reddy, Ebrahim, Shah, Dorairaj Prabhakaran, Ness, A   +23 more
core   +1 more source

Epigenomic Studies of Twins and Brain Diseases

, 2014
It has been generally accepted that complex diseases are caused by genetic and environmental factors; however, both genetic and epidemiological research programs are facing significant difficulties in explaining the etiopathogenesis of complex diseases.
Oh, Gabriel
core   +1 more source

DERMATOGLYPHIC METHODOLOGY FOR ESTABLISHING ZYGOSITY IN THE TWINS [PDF]

Journal of IMAB, 2020
Dermatoglyphic traits (DT) of the palms are an instrument, which is used in anatomy, anthropology, genetics and forensic services. DT can also be applied to medicine and in parts to the prevention of diseases, early diagnostic and establishing important ...
Ivan Maslarski, Galina Yaneva
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study. [PDF]

, 2012
PURPOSE: Association between genetic variants in complement factor H (CFH), factor B (CFB), component 2 (C2), and in the ARMS2/HTRA1 region with age-related macular degeneration (AMD) comes mainly from studies of European ancestry and case-control ...
Sundaresan, Periasamy, Ravindran, Ravilla D, Smeeth, Liam, Shanker, Ashwini, Chakravarthy, Usha, Fletcher, Astrid E, Nitsch, Dorothea, Vashist, Praveen, Nonyane, Bareng AS   +8 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source