Results 101 to 110 of about 263,960 (292)

O G-CSF na terapia do acidente vascular cerebral The potential role of G-CSF in stroke

Revista Brasileira de Hematologia e Hemoterapia, 2009
O fator estimulador de colônias granulocitárias (G-CSF) é uma glicoproteína descrita há mais de vinte anos, e é largamente utilizada para tratamento de estados neutropênicos e no transplante de medula óssea. O G-CSF estimula células-tronco hematopoéticas
Angelo L. Maset, Lilian Piron-Ruiz, Oswaldo T. Greco, Mario Lago, Alana F. C. Poloni, Milton A. Ruiz   +5 more
doaj  

AUTOLOGOUS STEM-CELL TRANSPLANTATION FOR MULTIPLE MYELOMA: EXPERIENCE OF A PUBLIC CENTER IN BRAZIL

Hematology, Transfusion and Cell Therapy, 2021
Introduction: Several novel therapies have been developed in recent years improving multiple myeloma (MM) treatment, although autologous hematopoietic stem cell transplantation (HSCT) remains a fundamental strategy in eligible patients. HSCT is even more
L Oliveira, MD Jacomassi, LJ Otuyama, BDGC Moraes, GA Martinez, L Mariano, V Rocha   +6 more
doaj  

Skin calcium deposits in primary familial brain calcification: A novel potential biomarker

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi, Giulia Bonato, Aleksandar Tushevski, Cinzia Bertolin, Francesco Cavallieri, Andrea Porzionato, Angelo Antonini, Leonardo Salviati, Miryam Carecchio   +8 more
wiley   +1 more source

TROMBOCITOPENIA AGUDA GRAVE APÓS INFUSÃO DE RITUXIMABE EM PACIENTE COM LINFOMA NÃO HODGKIN DE CÉLULAS B PERIFÉRICAS: RELATO DE CASO

Hematology, Transfusion and Cell Therapy, 2021
Objetivo: Relatar um caso de trombocitopenia aguda após segunda infusão de rituximabe em paciente com Linfoma Não Hodgkin (LNH) de células B periféricas, pequenas células. Descrição do caso: Masculino, branco, 41 anos, hipertenso, procedente de São Pedro
WF Silva, A Zago, G Bellaver, HA Castralli, AB Penha, PS Wieczorek, JC Salvador, PM Mariussi, RF Sales, NW Dembogurski   +9 more
doaj  

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier, Spyros Papapetropoulos, Andrew Marsh, Kelly Neelon, David Stiles, Ryan O'Mara, Evan A. Thackaberry, Marco Colonna, Raj Rajagovindan   +8 more
wiley   +1 more source

TRATAMENTO DE HEMARTROSES EM PACIENTES HEMOFÍLICOS GRAVES

Hematology, Transfusion and Cell Therapy, 2021
Introdução: As hemofilias A e B são doenças congênitas raras, recessivas ligadas ao X, causadas por falta ou deficiência de fator de coagulação VIII (FVIII) ou IX (FIX), respectivamente.
FV Costa, MEC Cordeiro, MC Antunes, RL Silva   +3 more
doaj  

Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]

In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles, France Meslé, Luisa Frova, Marilena Pappagallo, Michele Antonio Salvatore, Monica Pace, Viviana Egidi   +6 more
core  

Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron, Mandana Nikpour, Dylan Hansen, Susanna Proudman, Wendy Stevens, on behalf of the Australian Scleroderma Interest Group and the Canadian Scleroderma Research Group, Joanne Sahhar, Nava Ferdowsi, Kathleen Morrisroe, Laura Ross, Gene Siew Ngian, Jennifer Walker, Janet Roddy, Lauren Host, Mohammed Osman, Peter Docherty, Paul Fortin, Marvin Jacob Fritzler, Genevieve Gyger, Alena Ikic, Niall Jones, Elzbieta Kaminska, Maggie Larche, Sophie Ligier, Ada Man, Ariel Masetto, Janet Pope, David Robinson, Tatiana Sofia Rodriguez‐Reyna, Mianbo Wang   +29 more
wiley   +1 more source

ESTRUTURAÇÃO DE UMA PLATAFORMA BRASILEIRA DE MANUFATURA DE PRODUTO CELULAR AVANÇADO PARA USO EM CENÁRIO CLÍNICO

Hematology, Transfusion and Cell Therapy, 2021
O Hemocentro de Ribeirão Preto possui longa experiência na manufatura de células em Terapia Celular, através de uma infraestrutura com padrão de boas práticas que segue os critérios exigidos pela regulamentação brasileira.
SR Caruso, TR Fernandes, RMF Bolzoni, A Mizukami, MSA Neto, PVB Palma, CCO Bonaldo, MD Orellana, DT Covas, RLG Cunha, GC Santis   +10 more
doaj  

Considering the Risks and Costs of Solid Organ Xenotransplantation

Advanced Biology, EarlyView.
This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs, Janine McCarthy, Kristie Sullivan, James Craner, Brendan Parent, Ann Lam   +5 more
wiley   +1 more source