Results 91 to 100 of about 158,715 (307)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Anti-PF4 antibodies and their relationship with COVID infection

Hematology, Transfusion and Cell Therapy
Detecting anti-PF4 antibodies remains the golden diagnostic method for heparin-induced thrombocytopenia (HIT) diagnosis with high sensitivity and specificity.
Chieh Yang, Irene Wang, Akshit Chitkara, Jibin Swankutty, Rushin Patel, Samir V Kubba   +5 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Improved Leukemia Clearance After Adoptive Transfer of NK Cells Expressing the Bone Marrow Homing Receptor CXCR4R334X

HemaSphere, 2023
Filip Segerberg, Mélanie Lambert, Laura Sanz-Ortega, Agneta Andersson, Richard W. Childs, Mattias Carlsten   +5 more
doaj   +1 more source

The role of measuring peak systolic velocity of the middle cerebral artery blood flow and anti-K1 titre during pregnancy to detect foetuses with severe anaemia, foetal hydrops, and the requirement of intrauterine transfusion: A systematic review and meta-analysis

Hematology, Transfusion and Cell Therapy
The clinical manifestation of foetal anaemia caused by maternal Kell alloantibodies differs from that caused by non-Kell alloantibodies. Severe anaemia develops in the foetus in the early weeks of gestation; therefore, proper management and early ...
Mufleha Ahmed, Denise E. Jackson
doaj   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Letters from 1936, 1937, and 1938 from Dr. Wilkie H Blood to Zilla and Lorenzo Richards

, 1936
Letters dated December 1935 from Dr. Wilkie H Blood to Zilla and Lorenzo Richards concerning their children\u27s health: (1) Letter dated 9 January 1936 from Dr. Wilkie H.
Blood, Wilkie H.
core  

Lumped-Parameter Modelling of Cardiovascular System Dynamics under Different Healthy and Diseased Conditions [PDF]

, 2013
Cardiovascular disease is the most common cause of death in the modern society, and research into the diagnosis and treatment of cardiovascular diseases is an urgent task.
Shi, Yubing
core  

PET for Response Assessment to R-da-EPOCH in Primary Mediastinal Large B-cell lymphoma: Who Is Worthy to be Irradiated?

HemaSphere, 2023
Theodoros P. Vassilakopoulos, Alexia Piperidou, Zois Mellios, Evgenia Verigou, Eirini Katodritou, Christina Kalpadakis, Sotirios G. Papageorgiou, Chrysovalantou Chatzidimitriou, Vassilios Prassopoulos, Marina P. Siakantaris, Hara Giatra, Dimitrios Karantanis, Nikolaos Papathanasiou, Loukia Ligdi, Anastasia Kopsaftopoulou, Theoni Leonidopoulou, Vasileios Xanthopoulos, Stamatios Karakatsanis, Effimia Vrakidou, Sophia Chatziioannou, Dimitrios Drougkas, Eleftheria Hatzimichael, Gabriella Gainaru, Maria Palassopoulou, Maria Tsirogianni, Maria Kotsopoulou, Gerassimos Tsourouflis, Evangelia Skoura, Catherine Mainta, Evangelos Terpos, Christos Poziopoulos, Theodora Triantafyllou, Panayiotis Zikos, Argyro Koumarianou, Dimitra Liapi, Vassiliki Pappa, Evgenia Verrou, Panayiotis Tsirigotis, Vassiliki Labropoulou, Helen Papadaki, Ioannis Datseris, Argiris Symeonidis, Maria Bouzani, Maria Bakiri, Themis Karmiris, Maria K. Angelopoulou, Phivi Rondogianni   +46 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source