Results 101 to 110 of about 161,125 (296)

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

open access: yesAdvanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu   +19 more
wiley   +1 more source

SARS-CoV-2 Interstitial Pneumonia Treated With Tocilizumab in a Patient Affected by Classical Hodgkin Lymphoma

open access: yesHemaSphere, 2020
Chiara Rusconi   +10 more
doaj   +1 more source

P315: TP53 ALTERATIONS AND MRD REFINE PROGNOSIS OF ADULT KMT2A-REARRANGED B-ALL

open access: yesHemaSphere, 2023
Rathana Kim   +29 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

open access: yesAdvanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake   +5 more
wiley   +1 more source

A clinical and archaeological study of Schmorl’s Nodes: using clinical data to understand the past [PDF]

open access: yes, 2006
This study of Schmorl 's nodes in British populations past and present attempts to reach a better understanding of the origins and aetiology of Schmorl' s nodes and their impact upon the vertebral column in relation to age, sex, pre-existing skeletal ...
McNaught, Janet Mary   +1 more
core  

P325: APPLICATIONS OF HIGH-THROUGHPUT DRUG SCREENING AS DRUG REPURPOSING STRATEGY FOR POOR OUTCOME SUBGROUPS OF PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

open access: yesHemaSphere, 2023
Athanasios Oikonomou   +11 more
doaj   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky   +12 more
wiley   +1 more source

Selective allodepletion to improve anti-viral and anti-leukaemic responses after haploidentical transplantation [PDF]

open access: yes, 2009
Immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical SCT, but infection and leukaemic relapse remain problematic.
Samarasinghe, S, Samarasinghe, S.
core  

P335: PROGNOSTIC UTILITY OF NON-HOMOLOGOUS END JOINING DNA REPAIR PATHWAY GENES IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

open access: yesHemaSphere, 2023
Anita Chopra   +10 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

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