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“Hierarchy” and “Holacracy”; A Paradigm of the Hematopoietic System [PDF]

open access: yesCells, 2019
The mammalian hematopoietic system has long been viewed as a hierarchical paradigm in which a small number of hematopoietic stem cells (HSCs) are located at the apex. HSCs were traditionally thought to be homogeneous and quiescent in a homeostatic state.
Takafumi Yokota
doaj   +4 more sources

Contributions of Embryonic HSC-Independent Hematopoiesis to Organogenesis and the Adult Hematopoietic System [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
During ontogeny, the establishment of the hematopoietic system takes place in several phases, separated both in time and location. The process is initiated extra-embryonically in the yolk sac (YS) and concludes in the main arteries of the embryo with the
Wen Hao Neo   +3 more
doaj   +2 more sources

Obesity and inflammation and the effect on the hematopoietic system

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2014
Bone marrow is organized in specialized microenvironments known as 'marrow niches'. These are important for the maintenance of stem cells and their hematopoietic progenitors whose homeostasis also depends on other cell types present in the tissue ...
Bruno Deltreggia Benites   +2 more
doaj   +3 more sources

Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis. [PDF]

open access: yesCell Rep, 2022
Wang D   +12 more
europepmc   +2 more sources

The aged hematopoietic system promotes hippocampal-dependent cognitive decline. [PDF]

open access: yesAging Cell, 2020
Smith LK   +8 more
europepmc   +2 more sources

Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by 60Co γ ray irradiation

open access: yesFushe yanjiu yu fushe gongyi xuebao, 2023
Forty-eight mice were randomly divided into eight groups of six mice each. Group 1 was the control group, groups 2, 3, and 4 were the Potentilla anserina L drug groups, group 5 was the irradiation group, and groups 6, 7, and 8 were the irradiated ...
WU Daiyan   +6 more
doaj   +1 more source

Expert consensus on hematopoietic reconstruction strategies for radiation injury

open access: yesDi-san junyi daxue xuebao, 2021
Hematopoietic injury treatment is one of the main challenges in the treatment of radiation damage. In the face of mass casualty, how to make prompt and accurate diagnosis and evaluation for hematopoietic damage and then reconstitute hematopoiesis is of ...
Professional Committee of Military Radiation Medicine   +1 more
doaj   +1 more source

Common and Rare Hematological Manifestations and Adverse Drug Events during Treatment of Active TB: A State of Art

open access: yesMicroorganisms, 2021
Background: Tuberculosis (TB) can seriously affect the hematopoietic system, with involvement of both myeloid and lymphoid cell lines as well as plasma components.
Maria Letizia Minardi   +12 more
doaj   +1 more source

Single cell sequencing in the study of hematopoietic system: application and perspects

open access: yesDi-san junyi daxue xuebao, 2021
Single cell sequencing (SCS) is a technique for precise analysis of cells at an individual level, which provides a new perspective on the identification of individual cell types, functions, states and interactions with other cells, and greatly deepens ...
WANG Junping, CHEN Naicheng
doaj   +1 more source

Exosomal MiR-4261 mediates calcium overload in RBCs by downregulating the expression of ATP2B4 in multiple myeloma

open access: yesFrontiers in Oncology, 2022
BackgroundHypercalcemia induced by multiple myeloma (MM) affects the biological functions of excitable and non-excitable cells. However, red blood cells (RBCs) regulatory effect on calcium in hypercalcemia is still not fully understood.MethodsA total of ...
Sicheng Bian   +20 more
doaj   +1 more source

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