Results 11 to 20 of about 248,820 (244)

Deubiquitinase MYSM1 in the Hematopoietic System and beyond: A Current Review. [PDF]

Int J Mol Sci, 2020
Fiore A, Liang Y, Lin YH, Tung J, Wang H, Langlais D, Nijnik A.   +6 more
europepmc   +2 more sources

Exosomal MiR-4261 mediates calcium overload in RBCs by downregulating the expression of ATP2B4 in multiple myeloma

Frontiers in Oncology, 2022
BackgroundHypercalcemia induced by multiple myeloma (MM) affects the biological functions of excitable and non-excitable cells. However, red blood cells (RBCs) regulatory effect on calcium in hypercalcemia is still not fully understood.MethodsA total of ...
Sicheng Bian, Sicheng Bian, Xialin Zhang, Leilei Lin, Lili Sun, Lili Sun, Zhibo Guo, Zhibo Guo, Jie Pan, Jiangxia Cui, Hanbing Yao, Jing Xu, Zhuanghui Hao, Yuzhu Wang, Yuzhu Wang, Liguo Tong, Xingpeng Bu, Desheng Kong, Nianjiao Liu, Yinghua Li, Yinghua Li   +20 more
doaj   +1 more source

The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment

Frontiers in Immunology, 2017
Antibodies to different brain proteins have been recently found to be associated with an increasing number of different autoimmune diseases. They need to penetrate the blood–brain barrier (BBB) in order to bind antigens within the central nervous system (
Simone Mader, Lior Brimberg, Betty Diamond   +2 more
doaj   +1 more source

Leukemia risk and rate of radiation dose accumulation. Part 2: Comparative analysis of leukocytic indices and dynamics of peripheral blood values in relation to external gamma-exposure dose

Радиационная гигиена, 2020
The results of a retrospective analysis of leukocytic indices and dynamics of peripheral blood values in relation to external gamma-exposure dose among the personnel of the first atomic production facility in Russia were presented.
S. F. Sosnina, A. M. Yurkin, P. V. Okatenko, S. A. Rogacheva, E. A. Gruzdeva, M. E. Sokolnikov   +5 more
doaj   +1 more source

Sporadic multicentric lymphoma in a Nelore calf

Brazilian Journal of Veterinary Pathology, 2015
A case of sporadic multicentric lymphoma in a Nelore calf is reported. Anatomic presentation, age of affected animal, and cytology done on fine needle aspiration biopsy from lymph node supported a presumptive clinical diagnosis.
Alexandre O. Bezerra, Stephanie C. Lima, Marcelo A. Araújo, Valdemir A. Oliveira, Larissa G. Ávila, Claudio S. L. Barros   +5 more
doaj   +1 more source

Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells

Stem Cell Research & Therapy, 2021
Background Decades of efforts have attempted to differentiate the pluripotent stem cells (PSCs) into truly functional hematopoietic stem cells (HSCs), yet the problems of low differentiation efficiency in vitro and poor hematopoiesis reconstitution in ...
Wei Shan, Qin Yu, Yan Long, Qian Luo, Honghu Li, Yingli Han, Yulin Xu, Shan Fu, Xiangjun Zeng, Cong Wei, Yang Gao, Xiaoqing Li, Xia Li, Lifei Zhang, Lizhen Liu, Ming Chen, Pengxu Qian, He Huang   +17 more
doaj   +1 more source

Pathological and compensatory reactions in the blood system of small rodents exposed to chronic low dose ionizing radiation [PDF]

Ядерна фізика та енергетика
Changes in the blood systems of small rodents inhabiting for many generations the Chornobyl Exclusion Zone territories with a relatively low level of radionuclide pollution were studied.
A. I. Lypska, N. K Rodionova, N. M. Riabchenko, O. O. Burdo, V. A. Shytiuk   +4 more
doaj   +1 more source

Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC

Stem Cell Research & Therapy, 2022
Background Hematopoietic stem cells are able to self-renew and differentiate into all blood cell lineages. Hematopoietic stem cell transplantation is a mainstay of life-saving therapy for hematopoietic malignancies and hypoproliferative disorders.
Ning Wang, Chuxin Chen, Yang Cheng, Yingjie Fu, Zhiyong Zhong, Yu Yang, Ling Lv, Honglin Chen, Jian Huang, Yuyou Duan   +9 more
doaj   +1 more source

The CKS1/CKS2 Proteostasis Axis Is Crucial to Maintain Hematopoietic Stem Cell Function

HemaSphere, 2023
Long-term hematopoietic stem cells are rare, highly quiescent stem cells of the hematopoietic system with life-long self-renewal potential and the ability to transplant and reconstitute the entire hematopoietic system of conditioned recipients.
William Grey, Samantha Atkinson, Beatrice Rix, Pedro Casado, Linda Ariza-McNaughton, Cathy Hawley, Miriam L. Sopoena, Katherine S. Bridge, David Kent, Pedro R. Cutillas, Dominique Bonnet   +10 more
doaj   +1 more source

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. [PDF]

PLoS ONE, 2011
Elucidating the in vitro differentiation of human embryonic stem (ES) and induced pluripotent stem (iPS) cells is important for understanding both normal and pathological hematopoietic development in vivo.
Akira Niwa, Toshio Heike, Katsutsugu Umeda, Koichi Oshima, Itaru Kato, Hiromi Sakai, Hirofumi Suemori, Tatsutoshi Nakahata, Megumu K Saito   +8 more
doaj   +1 more source