Results 121 to 130 of about 279,800 (313)

IMPACTO DO NÚMERO DE TRANSFUSÕES PRÉVIAS NAS REAÇÕES TRANSFUSIONAIS IMEDIATAS: UM ESTUDO DE CASO CONTROLE DE 7763 TRANSFUSÕES EM HOSPITAL TERCIÁRIO DO SUL DO BRASIL

Hematology, Transfusion and Cell Therapy, 2020
C.F. Pithan, L. Sekine, C.A. Polanczyk, A. Vigo   +3 more
doaj   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

A importância do diagnóstico laboratorial clássico na identificação de variantes de hemoglobinas The importance of classical laboratorial diagnosis in the identification of variant hemoglobins

Revista Brasileira de Hematologia e Hemoterapia, 2005
Luciana S. Ondei, Paula J. A. Zamaro, Claudia R. Bonini-Domingos   +2 more
doaj   +1 more source

AVALIAÇÃO DO PERFIL SOROLÓGICO PARA DOENÇAS INFECCIOSAS TRANSMISSÍVEIS DE PACIENTES QUE TIVERAM CONCENTRADO DE CÉLULAS PROGENITORAS HEMATOPOÉTICAS CRIOPRESERVADOS PARA TRANSPLANTE DE MEDULA ÓSSEA AUTÓLOGO

Hematology, Transfusion and Cell Therapy, 2020
K.L. Prata, A.P.C. Funes, J.R. Luz, L.A. Costa, M.D.S.B.S. Furtado, M.C. Martins, N.G. Cruz, P.R.M.P. Pederzoli, R.K. Andrade, M.R.I.S. Libânio, A.R. Belisário   +10 more
doaj   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

LMA COM ACOMETIMENTO EXTRAMEDULAR EM PELE E GÂNGLIOS

Hematology, Transfusion and Cell Therapy, 2020
A.V.C. Paiva, J.P. Oliveira, M.E.S. Sousa, I.S.S.V. Duque, M.P. Silveira, R.N. Oliveira, S.B.A. Mattar, G.D. Mariano, G.B. Vallim, F.S. Camargo   +9 more
doaj   +1 more source

Impacto da inflamação na regulação do ferro e deficiência funcional de ferro Importance of inflammation on iron homeostasis and functional iron deficiency

Revista Brasileira de Hematologia e Hemoterapia, 2010
Deficiência funcional de ferro (Fe) pode ser definida como o desbalanço entre a quantidade necessária de Fe para a síntese de hemoglobina e o seu suprimento.
Maria Stella Figueiredo
doaj  

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source