Results 191 to 200 of about 161,125 (296)

Pharmacological Therapy in Patients With Gender Dysphoria: A Cohort Study in the Lazio Region, Italy. [PDF]

Pharmacoepidemiol Drug Saf
Belleudi V, Lopes S, Servadio M, Bellini A, Addis A.   +4 more
europepmc   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Autism Spectrum Disorder and Life Expectancy Among Medicaid Beneficiaries.

JAMA Netw Open
Li G, DiGuiseppi CG, Blanchard A, Russell MT, Ing C.   +4 more
europepmc   +1 more source

Gut microbiota as a therapeutic target in sepsis-induced multi-organ dysfunction: a review. [PDF]

Front Cell Infect Microbiol
Zhao X, Ma T, Yu J, Hu Y.
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Integrating mechanical cues in <i>in vitro</i> models of immune-related fibrotic diseases. [PDF]

Front Immunol
Song C, Zhu M, Li P, Mao Q, Zhu C, Li N, Zhang Y, Du Y, Long M.   +8 more
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Gut-reproduction axis: a new perspective on understanding pelvic inflammatory disease. [PDF]

Front Microbiol
Ma S, Wang M, Tan X, Shen C, Tao X, Sheng M, Zhang X, Xu Y, Zheng L.   +8 more
europepmc   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Advances in vascularized organoids. [PDF]

Chin Med J (Engl)
Shen L, Ma J, Wei X, Shi G, Deng H.
europepmc   +1 more source