Advanced Healthcare Materials, EarlyView.A dual‐crosslinking poly(ethylene glycol) (PEG) hydrogel is presented that rapidly solidifies and progressively adheres to tissue, achieving durable sealing of bile leaks. In hepatectomy models, this system prevents postoperative complications more effectively than conventional sealants, highlighting its translational potential as a safe and efficient ...
Kazuyoshi Matsubara +7 more
wiley +1 more source
Unveiling the gut-liver axis: the behind-the-scenes "manipulator" of human immune function. [PDF]
Front ImmunolLi P, Wang Y, Dong Y, Zhang X.
europepmc +1 more source
Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems
Advanced Healthcare Materials, EarlyView.Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei +6 more
wiley +1 more source
A Case of Psoas Abscess Diagnosed With Oral Bacteria as the Causative Pathogen. [PDF]
CureusUmemori K +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans +8 more
wiley +1 more source
Longitudinal Descriptive Analysis of Dynamic Changes in Safety Concerns in Japanese Risk Management Plans for Medicinal Products Over 8 Years After Approval. [PDF]
Ther Innov Regul SciIshiguro C, Sazawa M, Nonaka T.
europepmc +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
The role of copper dysregulation in Wilson disease: an expert opinion. [PDF]
Front Med (Lausanne)Stremmel W, Weiskirchen R.
europepmc +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Profiling of outpatients attending Centre for Rural Health, Nutakkhi, Andhra Pradesh, South India. [PDF]
J Family Med Prim CareGupta A +5 more
europepmc +1 more source