Results 221 to 230 of about 297,941 (307)

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

Advanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim, Yeojin Kim, Sanjita Paudel, In Young Kang, Suyeon Kim, Jeesoo Kim, Sunmi Park, Seung‐Hoi Koo, Hyun Sung Kim, Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee   +12 more
wiley   +1 more source

Preclinical Evaluation of Stable Integrin α_vβ₃-Specific [¹⁹⁸Au]Gold Nanoparticles for Tumor Therapy. [PDF]

Pharmaceuticals (Basel)
Davarci G, Wängler C, Eberhardt K, Tulessin M, Geppert C, Schirrmacher R, Fricker G, Mogler C, Pretze M, Wängler B.   +9 more
europepmc   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

The association between medication use and lifestyle factors in independently living older people: impact of Mediterranean diet and physical activity. [PDF]

JAR Life
Roeke L, Kennedy G, Meyer D, Kingsley M, Itsiopoulos C, Segal L, Minihane AM, Murphy KJ, Nguyen TA, Reddan JM, Verster JC, Pipingas A.   +11 more
europepmc   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Comorbidity Disease Pattern in Japanese Elderly Population: A Network-Based Analysis. [PDF]

Mayo Clin Proc Innov Qual Outcomes
Nojiri S, Urasaki W, Iwagami M, Nagao M, Uematsu T, Ishijima M, Daida H, Nishizaki Y.   +7 more
europepmc   +1 more source

Physical Intelligence in Small‐Scale Robots and Machines

Advanced Materials, EarlyView.
“Physical intelligence” (PI) empowers biological organisms and artificial machines, especially at the small scales, to perceive, adapt, and even reshape their complex, dynamic, and unstructured operation environments. This review summarizes recent milestones and future directions of PI in small‐scale robots and machines.
Huyue Chen, Metin Sitti
wiley   +1 more source

Hypothalamic Microglia as Dual Hubs Orchestrating Local and Systemic Homeostasis in the Periphery-Central-Periphery Axis. [PDF]

Cells
Liu Y, Jiang Q, Huang Y, Zhang X, Kang H, Yu C, Xia Y, Liu Y, Zhang H.   +8 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]

, 2017
Diamond, Michael S, et al,, Fox, Julie M, Sukulpovi-Petty, Soila   +3 more
core   +1 more source