Results 41 to 50 of about 3,014,077 (337)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The human health risk assessment from contaminated air in the oil-producing areas (on the example of Novoshehminsky Region of the Republic of Tatarstan) [PDF]

open access: yes, 2014
© 2014 AENSI Publisher All rights reserved. Based on the analysis of the monitoring results the air quality evaluation is provided and the incidence level of oil-producing Novosheshminsky region of the Republic of Tatarstan during the period of 2005-2009.
Latypova V., Novikova L., Stepanova N.
core  

Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection model [PDF]

open access: yes, 2020
Background: The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with potent anti-pathogenic and anti-inflammatory properties for future therapeutic and/or ...
Bereswill, Stefan   +7 more
core   +1 more source

Relationship between blood pressure and flow rate in arteries using a modified Windkessel model [PDF]

open access: yesarXiv, 2020
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow rate in an artery were examined.
arxiv  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

open access: yes, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H.   +3 more
core   +1 more source

Alterações moleculares em síndrome mielodisplásica Molecular abnormalities in myelodysplastic syndrome

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2006
A síndrome mielodisplásica (SMD) representa um grupo heterogêneo de doenças hematopoéticas clonais. As alterações cromossômicas observadas em SMD foram o ponto de partida para uma série de estudos para a caracterização da patogênese molecular nessa ...
Maria de Lourdes L. F. Chauffaille
doaj   +1 more source

Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease) [PDF]

open access: yes, 2018
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and chronic diseases(hypertension,dyslipidaemia,diabetes mellitus,chronic kidney disease,cardiovascular disease ...
arxiv   +1 more source

THE RELATION OF THE SPLEEN TO BLOOD DESTRUCTION AND REGENERATION AND TO HEMOLYTIC JAUNDICE

open access: yesJournal of Experimental Medicine, 1915
These experiments indicate, therefore, that when hemoglobin is set free in the portal circulation a larger amount is held by the liver and converted rapidly into bile pigment than is the case when it is set free in the general circulation, and that ...
Xil The I M P O R T A N C E In T H E Production Of H E   +2 more
semanticscholar   +1 more source

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