Results 41 to 50 of about 263,960 (292)

Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection model [PDF]

open access: yes, 2020
Background: The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with potent anti-pathogenic and anti-inflammatory properties for future therapeutic and/or ...
Bereswill, Stefan   +7 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Linfomas pulmonares: avaliação por tomografia computadorizada Pulmonary lymphomas: evaluation by computed tomography

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2004
This paper describes the tomographic appearance of pulmonary lymphomas. We studied the thoracic computed tomographies of ten patients with biopsy-proven diagnoses non-Hodgkin's and Hodgkin's disease. The most common radiologic findings in this series are
Edson Marchiori   +2 more
doaj   +1 more source

Improvement in pain-related quality of life in patients with hemophilia A treated with rFVIIIFc individualized prophylaxis: post hoc analysis from the A-LONG study

open access: yesTherapeutic Advances in Hematology, 2022
Background: Pain, a common symptom of hemophilia, begins early in life primarily due to joint bleeding. Recurrent bleeding adversely affects patients’ pain-related physical functioning, which can negatively impact their quality of life (QoL).
John Pasi   +6 more
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Mantle cell lymphoma management trends and novel agents: where are we going?

open access: yesTherapeutic Advances in Hematology, 2022
The heterogeneity in disease pathology, the unpredictability in disease prognosis, and the variability in response to therapy make mantle cell lymphoma (MCL) a focus of novel therapeutic development.
Jeffrey J. Pu   +3 more
doaj   +1 more source

Indications for Synergetic and Antagonistic Effects between Trace Elements in The Environment to Human Health [PDF]

open access: yes, 2007
The objective of this work was to investigate the interactions between the level of concentrations of Ca, V, Cr, Mn, Fe, Ni, Cu, Zn, As and Pb in potable water, soil, vegetation and school children hair and disease incidences of neoplasms, diseases of ...
Ante Kutle   +3 more
core   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Chimeric antigen receptor (CAR) T-cell treatment for mantle cell lymphoma (MCL)

open access: yesTherapeutic Advances in Hematology, 2022
Mantle cell lymphoma (MCL) is a rare B-cell malignancy that remains challenging to treat with high rates of relapse. Frontline strategies range from intensive chemotherapy followed by consolidation with autologous stem cell transplant (ASCT), to less ...
Bushra Tbakhi, Patrick M. Reagan
doaj   +1 more source

Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach [PDF]

open access: yes, 2014
Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane.
Choong, Y. S.   +8 more
core   +1 more source

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