Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
The human health risk assessment from contaminated air in the oil-producing areas (on the example of Novoshehminsky Region of the Republic of Tatarstan) [PDF]
© 2014 AENSI Publisher All rights reserved. Based on the analysis of the monitoring results the air quality evaluation is provided and the incidence level of oil-producing Novosheshminsky region of the Republic of Tatarstan during the period of 2005-2009.
Latypova V., Novikova L., Stepanova N.
core
Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection model [PDF]
Background: The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with potent anti-pathogenic and anti-inflammatory properties for future therapeutic and/or ...
Bereswill, Stefan+7 more
core +1 more source
Relationship between blood pressure and flow rate in arteries using a modified Windkessel model [PDF]
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow rate in an artery were examined.
arxiv
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H.+3 more
core +1 more source
A síndrome mielodisplásica (SMD) representa um grupo heterogêneo de doenças hematopoéticas clonais. As alterações cromossômicas observadas em SMD foram o ponto de partida para uma série de estudos para a caracterização da patogênese molecular nessa ...
Maria de Lourdes L. F. Chauffaille
doaj +1 more source
Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease) [PDF]
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and chronic diseases(hypertension,dyslipidaemia,diabetes mellitus,chronic kidney disease,cardiovascular disease ...
arxiv +1 more source
THE RELATION OF THE SPLEEN TO BLOOD DESTRUCTION AND REGENERATION AND TO HEMOLYTIC JAUNDICE
These experiments indicate, therefore, that when hemoglobin is set free in the portal circulation a larger amount is held by the liver and converted rapidly into bile pigment than is the case when it is set free in the general circulation, and that ...
Xil The I M P O R T A N C E In T H E Production Of H E+2 more
semanticscholar +1 more source