Results 71 to 80 of about 3,014,077 (337)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

A case of passenger lymphocyte syndrome following minor ABO incompatible renal transplantation

open access: yesAsian Journal of Transfusion Science, 2014
Immune hemolysis is one of the adverse effects that can occur following solid organ transplantation. Understanding the clinical settings and the various causes is necessary for prompt diagnosis and appropriate management.
Anju Dubey   +3 more
doaj   +1 more source

Sickle-cell disease: a call to action

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 2015
The inherited disorders of haemoglobin are the commonest monogenic diseases. It has been estimated that over 300 000 babies are born each year with one of these conditions, either sickle-cell disease or severe forms of thalassaemia.1 Normal adult ...
F. Piel, D. Weatherall
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Lentivector Transduction Improves Outcomes Over Transplantation of Human HSCs Alone in NOD/SCID/Fabry Mice [PDF]

open access: yes, 2012
Fabry disease is a lysosomal storage disorder caused by a deficiency of a-galactosidase A (a-gal A) activity that results in progressive globotriaosylceramide (Gb(3)) deposition.
Au, Bryan C. Y.   +7 more
core   +1 more source

Ruxolitinib In The Treatment Of Polycythemia Vera: An Update On Health-Related Quality Of Life And Patient-Reported Outcomes

open access: yesJournal of Blood Medicine, 2019
Shashank Cingam,1 Lainey Flatow-Trujillo,2 Leslie A Andritsos,1 Cecilia Arana Yi1 1University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA; 2Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM,
Cingam S   +3 more
doaj  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

The roles of endoglin gene in cerebrovascular diseases. [PDF]

open access: yes, 2017
Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core   +2 more sources

Linfomas não-Hodgkin extranodais em Salvador-Bahia: aspectos clínicos e classificação histopatológica segundo a OMS-2001 Extranodal non-Hodgkins lymphomas in Salvador, Brazil: clinical aspects and histopathological classification according to the WHO-2001 guidelines

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2008
Linfomas não-Hodgkin (LNH) extranodais representam cerca de um terço de todos os linfomas e atualmente apresentam taxa de incidência maior que a de linfomas nodais.
Marinho M. Silva Neto   +2 more
doaj   +1 more source

A Framework for a Smart Social Blood Donation System Based on Mobile Cloud Computing [PDF]

open access: yesHealth Informatics -- An International Journal (HIIJ), vol. 3, no. 4, pp:1-10,2014, 2014
Blood Donation and Blood Transfusion Services (BTS) are crucial for saving people lives. Recently, worldwide efforts have been undertaken to utilize social media and smartphone applications to make the blood donation process more convenient, offer additional services, and create communities around blood donation centers.
arxiv  

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