Results 71 to 80 of about 291,418 (306)

IL-4Rα (rs1801275) A>G polymorphism in Egyptian immune thrombocytopenia (ITP) patients: a single center experience

Hematology, Transfusion and Cell Therapy
Introduction: Chronic immune thrombocytopenia (cITP) is characterized by dysregulation of the immune response. Until recently, the role of Th2-related cytokine gene polymorphisms was unclear.
Mohamed Abdelkader Morad, Noha A. Doudar, Nehad Tawfeek, Maha Yacoub, Taha Azoz, Doaa El Demerdash   +5 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Human leukocyte antigen immunization in transfusion-dependent Moroccan patients with beta-thalassemia major: prevalence and risk factors

Hematology, Transfusion and Cell Therapy
Introduction: Beta-thalassemia major patients need a regular blood transfusion to have an initial normal growth. However, these patients have an increased risk of developing alloantibodies. Our main goal was to study HLA alloimmunization in Moroccan Beta-
Sanae Ouadghiri, Kaoutar El Morabit, Naoual Elansari, Ouafae Atouf, Maria Elkababri, Laila Hessissen, Malika Essakalli   +6 more
doaj   +1 more source

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Unveiling the Hidden Burden: From EPICOVIDEHA to EPIFLUEHA, Exploring the Epidemiology of Respiratory Viral Infections in Hematological Patients

HemaSphere, 2023
Jon Salmanton-García, Francesco Marchesi, Federico Itri, Francesca Farina, Martin Hoenigl, Raúl Córdoba, Shaimma El-Ashwah, Alessandro Busca, Marianna Criscuolo, Oliver A. Cornely, Livio Pagano   +10 more
doaj   +1 more source

ABO blood group discrepancies in blood donor and patient samples at a tertiary care oncology centre: analysis and serological resolution

Hematology, Transfusion and Cell Therapy
Introduction: In serological testing, determination of ABO grouping requires both antigen typing for A and B antigens and screening of serum or plasma for A and B antibodies.
Priti Desai, Anisha Navkudkar, Sunil Rajadhyaksha   +2 more
doaj   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Dental tissues of sickle cell anemia and its impact on the quality of life related to oral health

Hematology, Transfusion and Cell Therapy
Objective: The aim of this study was to determine the association between dental tissues and sickle cell anemia (SCA) and how it impacts the quality of life related to oral health.
Danny Kanyana Makolo, Alphonse Mutombo Mutombo, Fidele Nyimi Bushabu, Grace Paka Lubamba, Baruch Kabungu Yemweni, Ediz Ekofo Inganya, Patrick Sekele Marob, Em Kalala Kazadi, Jean Marie Kayembe Bukama, Augustin Mantshumba Milolo   +9 more
doaj   +1 more source

The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]

, 1995
In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G, Klein, S, Kriegsfeld, Lance, Nelson, R   +3 more
core   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source