Environmental Health and Preventive Medicine, 2013 The Hokkaido Study on Environment and Children’s Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940).
R. Kishi +12 more
semanticscholar +1 more source
The Effect of Drug Vintage on Survival: Micro Evidence from Puerto Rico's Medicaid Program [PDF]
Using micro data on virtually all of the drugs and diseases of over 500,000 people enrolled in Puerto Rico's Medicaid program, we examine the impact of the vintage (original FDA approval year) of drugs used to treat a patient on the patient's 3-year ...
Frank R. Lichtenberg
core
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
High PD-L1 expression is associated with unfavorable clinical features in myelodysplastic neoplasms
Hematology, Transfusion and Cell TherapyAbstatct: Introduction: Immune checkpoints are regulators of the immune system response that allow self-tolerance. Molecules such as Programmed Cell Death Protein 1 (PD-1) and its Ligand (PD-L1) participate in the immune checkpoint by signaling co ...
Leticia Rodrigues Sampaio +8 more
doaj +1 more source
Multimodal Image Analysis of Chronic Leukemic Lymphoproliferative Disorders and the Hypothesis of »Single« and »Multiple« Programmed Stops in the Development of Typical and Atypical Forms of Leukemias and Lymphomas [PDF]
, 2010 The study consisted of morphometric analysis, assessment of the argyrophilic nucleolar organization region (AgNOR) characteristics, and image cytometry (ICM) in different tumor mass compartments: bone marrow (BM), peripheral blood (PB) and lymph nodes ...
Biljana Jelić Puškarić +5 more
core +2 more sources
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Factores de riesgo cardiovascular y su relación con la progresión de la enfermedad venosa crónica
Revista Mexicana de AngiologíaAntecedentes: La progresión de la enfermedad venosa crónica (EVC) suele estar ligada a factores de riesgo que son motivo de investigación aun sin asociación clara.
Leopoldo E. Padilla-Hernández +7 more
doaj +1 more source
Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]
In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles +6 more
core
Arthritis Care &Research, EarlyView.Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech +4 more
wiley +1 more source
Elevated Transferrin at High Altitude: Trick or Treat?
HemaSphere, 2023 Francesca Vinchi
doaj +1 more source