Results 201 to 210 of about 179,114,418 (259)

Review Article: Implementation Challenges in Helicobacter pylori Management: Bridging Evidence and Real-World Practice. [PDF]

Aliment Pharmacol Ther
Quach DT, Liou JM, Gisbert JP, Leung WK, Moss SF, Fallone CA, Katelaris P, Schulz C, Kayamba V, Zhou L, Vu NTH, Vilaichone RK, Miftahussurur M, Setshedi M, Riquelme A, Yadegar A, Lee YY, Ishibashi F, Jung HY, Coelho LG, Suzuki H, Lee YC, Megraud F, Mahachai V, Sugano K, Malfertheiner P.   +25 more
europepmc   +1 more source

Clinical Utility of Anti‐reflux Mucosal Intervention for Refractory Gastroesophageal Reflux Disease in Patients With a Hiatal Hernia

DEN Open, Volume 7, Issue 1, April 2027.
Abstract Background Surgical fundoplication is the standard treatment for refractory gastroesophageal reflux disease (GERD) with large (≥3 cm) hiatal hernias; however, its invasiveness is problematic in older adults and high‐risk patients. Anti‐reflux mucosal intervention (ARMI) is a less invasive endoscopic alternative; however, patients with large ...
Masachika Saino, Haruhiro Inoue, Kei Ushikubo, Miyuki Iwasaki, Kazuki Yamamoto, Yohei Nishikawa, Ippei Tanaka, Hidenori Tanaka, Mayo Tanabe, Satoshi Abiko, Boldbaatar Gantuya, Manabu Onimaru, Shiro Oka   +12 more
wiley   +1 more source

Liver Aging Index: A Noninvasive Score for Liver Biological Aging and Liver-Related Outcomes in Multicohorts. [PDF]

Aging Cell
Wu Z, Wu S, Song S, Huang Y, Yu C, Sun D, Pei P, Yang L, Chen Y, Du H, Walters R, Millwood I, Xu H, Yang X, Chen J, Kim SU, Petta S, Nakajima A, Tsochatzis E, Boursier J, Bugianesi E, Chan WK, Romero-Gomez M, Calleja JL, de Lédinghen V, Castéra L, Sanyal AJ, Goh GB, Newsome PN, Fan JG, Lai M, Zhou XD, Chen Z, Lv J, Li L, Wong VW, Zheng MH, Pang Y, China Kadoorie Biobank Collaborative Group and VCTE‐Prognosis Study Group.   +38 more
europepmc   +1 more source

Musculoskeletal (Mal)adaptations in Response to a > 30 000‐km Running Challenge

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Ultra‐endurance sports are increasingly popular, yet the long‐term physiological consequences of sustained extreme training loads remain poorly understood. In particular, the effects of prolonged ultra‐endurance exercise on skeletal muscle structure, function and molecular remodelling are largely unknown.
Tomas Venckunas, Thomas Chaillou, Leonardo Cesanelli, Danguole Satkunskiene, Saulius Rutkauskas, Audrius Snieckus, Petras Minderis, Darja Nikitina, Jurgita Skieceviciene, Juozas Kupcinskas, Lorenz Webersberger, Johanna T. Lanner, Mantas Mickevicius, Birutė Gumauskiene, Asta Kuzmickaite, Andrejus Subocius, Sigitas Kamandulis   +16 more
wiley   +1 more source

Novel therapeutic ultrathin endoscope facilitates endoscopic intermuscular dissection for gastrointestinal stromal tumor adjacent to the anus. [PDF]

Endoscopy
Li T, Huang S, Liao S, Guo Q, Zhong E, Zhang Y, Wang H.   +6 more
europepmc   +1 more source

Bile Acid Metabolism as a Unifying Readout for Diet, Microbiome Function, and Gastrointestinal Disease

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Dietary components shape the gut microbiome, which modifies bile acids through transformations. The resulting bile acid pool is sensed by host receptors to regulate immunity, metabolism, and intestinal function. Targeted bile acid measurements provide a unifying readout to study diet‐microbiome interactions and to develop next‐generation dietary ...
Jason Dichter
wiley   +1 more source

Persistent health inequality in the global burden of digestive diseases attributable to risk factors: a systematic analysis for the Global Burden of Disease Study 2021. [PDF]

BMJ Public Health
Zhong P, Su B, Ren Z, Wu Y, Song Z, Zheng X.   +5 more
europepmc   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

A Quality Improvement Initiative to Increase Helicobacter pylori Testing and Eradication Among Patients Diagnosed With Peptic Ulcer Disease in a U.S. Safety-Net Hospital. [PDF]

J Clin Gastroenterol
Abdel-Jaber W, Padilla F, Gomez Cifuentes JD, Agrawal N, Sealock RJ, El-Serag HB, Tan MC.   +6 more
europepmc   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1563-1574, September 2026.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source