Results 201 to 210 of about 137,095 (246)

Burden of Invasive Fungal Diseases in Patients With Alcohol‐Related Hepatitis and Organ Failure

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Between 2012 and 2021 in France, invasive fungal diseases affected 1 in 50 patients with alcohol‐related hepatitis and at least two hepatic or extrahepatic complications, with substantially higher mortality than bacterial pneumonia. These findings support targeted screening and early antifungal strategies in this population, as currently recommended ...
Charlotte Mouliade   +9 more
wiley   +1 more source

Comparative Risk of Hepatitis B Virus Reactivation in Patients Receiving Immune Checkpoint Inhibitors or Tyrosine Kinase Inhibitors for Liver Cancer

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a cohort of 1596 liver cancer patients with either current or prior HBV infection undergoing systemic therapy in Hong Kong, the risk of HBV reactivation during immune checkpoint inhibitor treatment was low when adequate antiviral prophylaxis was administered, irrespective of HBV infection status.
Dorothy Cheuk‐Yan Yiu   +9 more
wiley   +1 more source

Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a multi‐centre study of obeticholic acid in primary biliary cholangitis, 45% discontinued the drug over 4 years, with 11% moving to combination therapy (fibrates). Of those continuing, response rates increased from 37% (1 year) to 55% (4 years). Non‐response at 12 months and cirrhosis were independent predictors of liver‐related events.
Nadir Abbas   +18 more
wiley   +1 more source

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang   +15 more
wiley   +1 more source

Minimum standards for training in colorectal endoscopic mucosal resection among advanced endoscopy trainees

open access: yesEndoscopy International Open
Dennis Yang   +24 more
doaj   +1 more source

Prevalence of Opioid Use and Associated Healthcare Outcomes in Rome IV Irritable Bowel Syndrome in the United Kingdom

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
One in five people with Rome IV irritable bowel syndrome use opioids on a regular basis. Compared with non‐users, opioid users had worse quality of life, greater psychological impairment, and higher direct healthcare costs. ABSTRACT Background The United Kingdom (UK) has one of the highest worldwide opioid prescription rates per capita.
Mohsin F. Butt   +6 more
wiley   +1 more source

The Bethesda ERCP Skills Assessment Tool (BESAT) can reliably differentiate endoscopists of different experience levels

open access: yesEndoscopy International Open
Kevin Liu   +20 more
doaj   +1 more source

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