Results 81 to 90 of about 268,573 (327)

Puerarin: a hepatoprotective drug from bench to bedside

Chinese Medicine
Pueraria is a time-honored food and medicinal plant, which is widely used in China. Puerarin, the main component extracted from pueraria, has a variety of pharmacological characteristics.
Yi-Xiang He, Meng-Nan Liu, Hao Wu, Qi Lan, Hao Liu, Maryam Mazhar, Jin-Yi Xue, Xin Zhou, Hui Chen, Zhi Li   +9 more
doaj   +1 more source

DISEASES OF THE DIGESTIVE SYSTEM: PRIMARY DISABLEMENT IN THE IRKUTSK REGION

Acta Biomedica Scientifica, 2017
Materials and methods. The population-based cohort analysis was performed of the database of primary disabled in Irkutsk region due to the DDS for the period of 2013-2015. Morbidity rate of primary disablement was calculated for 10 000 of the population;
I. L. Petrunko, V. I. Soklakova, A. A. Cherkasova, N. V. Sergeeva   +3 more
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Analysis of the actual nutrition status of servicemen of the Transcarpathian region who participated in the ATO and its influence on the development of the pathology of the digestive organs

Journal of Geography, Politics and Society, 2018
The influence of lifestyle factors, namely rationality of nutrition, on the health of the population is the strongest relative to other risk factors that may be manifested by the development and complication of diseases of the digestive system. This gain
Ivan M. Rogach, Angelika O. Keretsman, Ivan I. Gadzhega   +2 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

The Main Symptoms and Syndromes in Diseases of the Digestive System

Gastroenterologìa, 2016
The article presents the main clinical symptoms and syndromes that occur in various diseases of the abdominal cavity. Both widely known and rare symptoms of gastroenterological dise­ases are presented.
I.N. Kononov, M.V. Chalyi, О.M. Kovalenko   +2 more
doaj   +1 more source

CHARACTERISTICS OF VITAMIN COMPOSITION OF MEDICINAL PLANT RAW MATERIALS FOR CREATING FOOD ADDITIVES WITH A DIGESTIVE PROFILE

Bulletin of the South Ural State University Series Food and Biotechnology
There is a problem that in the middle of the 21st century, digestive system diseases caused by insufficient supply of micronutrients and low quality of food products will occupy one of the leading places among pathologies. The article formulates the role
T. Ivanova, O. Evdokimova
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Bacterial extracellular vesicles: emerging mediators of gut-liver axis crosstalk in hepatic diseases

Frontiers in Cellular and Infection Microbiology
Bacterial Extracellular Vesicles (BEVs) are key mediators of cross-talk between gut microorganisms and host organs, playing an especially important role in the gut-liver axis.
Yutong Zhou, Yong Sun, Pengsheng Yin, Shi Zuo, Shi Zuo, Shi Zuo, Haiyang Li, Haiyang Li, Haiyang Li, Kun Cao, Kun Cao, Kun Cao   +11 more
doaj   +1 more source

Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys

Microbiome, 2020
Background The microbiota plays an important role in HIV pathogenesis in humans. Microbiota can impact health through several pathways such as increasing inflammation in the gut, metabolites of bacterial origin, and microbial translocation from the gut ...
Anna J. Jasinska, Tien S. Dong, Venu Lagishetty, William Katzka, Jonathan P. Jacobs, Christopher A. Schmitt, Jennifer Danzy Cramer, Dongzhu Ma, Willem G. Coetzer, J. Paul Grobler, Trudy R. Turner, Nelson Freimer, Ivona Pandrea, Cristian Apetrei   +13 more
doaj   +1 more source