Results 81 to 90 of about 496,181 (282)

Association of mutations in the basal core promoter and pre-core regions of the hepatitis B viral genome and longitudinal changes in HBV level in HBEAG negative individuals: Results from a cohort study in northern Iran [PDF]

, 2015
Background: Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear.
Besharat, S., Freedman, N.D., Katoonizadeh, A., Malekzadeh, R., Mohamadkhani, A., Moradi, A., Poustchi, H., Roshandel, G.   +7 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Analysis of the actual nutrition status of servicemen of the Transcarpathian region who participated in the ATO and its influence on the development of the pathology of the digestive organs

Journal of Geography, Politics and Society, 2018
The influence of lifestyle factors, namely rationality of nutrition, on the health of the population is the strongest relative to other risk factors that may be manifested by the development and complication of diseases of the digestive system. This gain
Ivan M. Rogach, Angelika O. Keretsman, Ivan I. Gadzhega   +2 more
doaj   +1 more source

Our Impressive Immune System: More Than a Defense [PDF]

, 2014
Most likely the immune system was put into place in the original human body design. We know from Exodus 20:11 and other verses that God completed His work of creation in six days.
Conrad, Jason, Gillen, Alan L.
core   +1 more source

Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats [PDF]

, 2014
Chronic psychological stress is a prominent risk factor involved in the pathogenesis of many complex diseases, including major depression, obesity, and type II diabetes.
Abel, Adler, Ahima, Archuleta, Barsy, Bartness, Bartolomucci, Bartolomucci, Bjorntorp, Bose, Bost, Bradesi, Bray, Buren, Cai, Christiansen, Depke, Despres, Desreumaux, Edgar, Fortuno, Gonnissen, Griffin, Hawley, Hennings, Hirosumi, Hotamisligil, Hotamisligil, Hotamisligil, Karagiannides, Karagiannides, Kim, Kyrou, Lamounier-Zepter, Lehrke, Ma, Marra, Morino, Nieuwenhuizen, Ogden, Pechlivanova, Perrini, Razzouk, Rodriguez, Shively, Slentz, Speaker, Stubbs, Tanti, van Reedt Dortland, Willner, Yu, Yuan, Zhang   +53 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Bacterial extracellular vesicles: emerging mediators of gut-liver axis crosstalk in hepatic diseases

Frontiers in Cellular and Infection Microbiology
Bacterial Extracellular Vesicles (BEVs) are key mediators of cross-talk between gut microorganisms and host organs, playing an especially important role in the gut-liver axis.
Yutong Zhou, Yong Sun, Pengsheng Yin, Shi Zuo, Shi Zuo, Shi Zuo, Haiyang Li, Haiyang Li, Haiyang Li, Kun Cao, Kun Cao, Kun Cao   +11 more
doaj   +1 more source

Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system [PDF]

, 2020
Yue Zhang, Fanhong Zeng, Xu Han, Jun Weng, Yi Gao   +4 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. [PDF]

, 2015
The majority of those who drink excessive amounts of alcohol do not develop pancreatic disease. One overarching hypothesis is that alcohol abuse requires additional risk factors, either environmental or genetic, for disease to occur.
Lugea, Aurelia, Pandol, Stephen J, Waldron, Richard T   +2 more
core   +1 more source