Results 61 to 70 of about 335,393 (290)

The morphology and application of stem cells in digestive system surgery

, 2021
Background: Stem cells constitute a group of cells which possess the ability to self-renew as well as the capacity to differentiate into a vast number of different cells within the human organism.
Grochowski, C.; Department of Anatomy, Medical University of Lublin, Poland, Sitarz, M.; Department of Conservative Dentistry with Endodontics, Medical University of Lublin, Poland, Baj, J.; Department of Anatomy, Medical University of Lublin, Poland, Pucułek, M.; Department of Anatomy, Medical University of Lublin, Poland, Portincasa, P.; Clinica Medica “A. Murri”, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Poland, Radzikowska, E.; Department of Plastic Surgery, Saint Elisabeth Hospital in Warsaw, Poland   +5 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Diseases of the digestive system

Kazan medical journal, 1934
In the preface to his book, Prof. R.A. Luria writes: "Diseases of the digestive organs are undoubtedly the most frequent diseases with which the therapist has to deal. It is impossible not to agree with this, as well as with the idea that this area of internal medicine is the least familiar to a wide range of physicians.
openaire   +1 more source

Peculiarities of the digestive system organs’ triad diseases сlinic and treatment

, 2019
Проведено дослідження клініки тріади захворювань органів системи травлення з обґрунтуванням запропонованого нами методу лікування у 40 хворих при поєднанні дуоденальної виразки, холециститу і панкреатиту.
Dudchenko, M. O., Сорокіна, Світлана Іванівна, Kryvoruchko, I. G., Третяк, Наталья Григорьевна, Tretiak, N. G., Дудченко, Максим Александрович, Криворучко, Іван Григорович, Третяк, Наталія Григорівна, Сорокина, Светлана Ивановна, Дудченко, Максим Андрійович, Дудченко, Максим Олександрович, Dudchenko, M. A., Дудченко, Максим Андреевич, Sorokina, S. I., Криворучко, Иван Григорьевич   +14 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study

Chinese Medical Journal
. Background:. Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on the burden of digestive system diseases in China are lacking.
Zhiyuan Cheng, Tinglu Wang, Yunfei Jiao, Jinlei Qi, Xun Zhang, Siwei Zhou, Lei Xin, Rong Wan, Maigeng Zhou, Zhaoshen Li, Luowei Wang, Yuanyuan Ji   +11 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Puerarin: a hepatoprotective drug from bench to bedside

Chinese Medicine
Pueraria is a time-honored food and medicinal plant, which is widely used in China. Puerarin, the main component extracted from pueraria, has a variety of pharmacological characteristics.
Yi-Xiang He, Meng-Nan Liu, Hao Wu, Qi Lan, Hao Liu, Maryam Mazhar, Jin-Yi Xue, Xin Zhou, Hui Chen, Zhi Li   +9 more
doaj   +1 more source

TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis

Frontiers in Immunology
BackgroundDistant metastasis remains a major reason for the high recurrence and mortality of colorectal cancer (CRC). However, the underlying molecular mechanisms driving metastasis in CRC remain poorly understood.
Xiaotian Song, Xiaotian Song, Shuai Xu, Shuai Xu, Dan Song, Juan Wang, Bin Bai, Yanxin An, Bin Yang, Shiqi Wang, Qingchuan Zhao, Pengfei Yu   +11 more
doaj   +1 more source

DISEASES OF THE DIGESTIVE SYSTEM: PRIMARY DISABLEMENT IN THE IRKUTSK REGION

Acta Biomedica Scientifica, 2017
Materials and methods. The population-based cohort analysis was performed of the database of primary disabled in Irkutsk region due to the DDS for the period of 2013-2015. Morbidity rate of primary disablement was calculated for 10 000 of the population;
I. L. Petrunko, V. I. Soklakova, A. A. Cherkasova, N. V. Sergeeva   +3 more
doaj   +1 more source