Results 51 to 60 of about 335,393 (290)

Obesity as a risk factor for diseases of the digestive system

Терапевтический архив, 2021
Currently, the global prevalence of obesity among the worlds adult population is about 650 million people, which makes it possible to consider this chronic metabolic disease as a non-infectious pandemic of the 21st century.
Dmitry N. Andreev, Yury A. Kucheryavyy
doaj   +1 more source

Lactobacillus reuteri in digestive system diseases: focus on clinical trials and mechanisms [PDF]

, 2023
ObjectivesDigestive system diseases have evolved into a growing global burden without sufficient therapeutic measures. Lactobacillus reuteri (L.
Yizhe Ma, Zichen Luo, Zhimin Xu, Yijing Peng, Yifan Jiang, Renqiang Yu   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Role of yoga in the management of digestive system disorders

Environment Conservation Journal, 2017
A healthy digestive system is the key to total health. Digestive system diseases contribute a big proportion of all pathologies. Yoga is being recognised worldwide as the solution to these problems.
Manorma Singh
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway

Frontiers in Nutrition
IntroductionAlcoholic liver disease (ALD) is a pathological state of the liver caused by longterm alcohol consumption. Recent studies have shown that the modulation of the gut microbiota and its metabolic products, specifically the short-chain fatty ...
Mingyun Tang, Mingyun Tang, Long Zhao, Long Zhao, Fuchun Huang, Fuchun Huang, Tiangang Wang, Tiangang Wang, Xu Wu, Shanshan Chen, Shanshan Chen, Juan Fu, Juan Fu, Chaoli Jiang, Chaoli Jiang, Shulin Wei, Shulin Wei, Xuseng Zeng, Xuseng Zeng, Xiaoling Zhang, Xiaoling Zhang, Xin Zhou, Xin Zhou, Mei Wei, Zhi Li, Zhi Li, Zhi Li, Guohui Xiao, Guohui Xiao   +28 more
doaj   +1 more source

Examining the relationship between secondhand smoke and non-malignant digestive system diseases: Mendelian randomization evidence

Introduction Secondhand smoke (SHS) may exacerbate the global disease burden, particularly in workplace settings. Observational studies have implicated SHS as a risk factor for various non-malignant digestive system diseases (NMDSD), yet establishing a ...
Yujun Yu, Yongyun Jin
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use

Frontiers in Pharmacology
IntroductionIntegrative medicine combining traditional Chinese medicine (TCM) with biomedicine has become a notable approach for treating acute pancreatitis (AP).
Xin Zhou, Xin Zhou, Yu Yang, Ya-Li Liu, Ya-Li Liu, Wei-An Hao, Wei-An Hao, Xin-Yi Ao, Xin-Yi Ao, Jian-Qin Liu, Jian-Qin Liu, Yang Zhang, Zhi Li, Zhi Li, Zhi Li   +14 more
doaj   +1 more source

Dynamics of prevalence of diseases of the digestive system among the population of different age groups in conditions of social stress [PDF]

, 2018
Objective: to analyze the prevalence of digestive diseases during social stress among the population of different age groups (young, mature, elderly / old). Material and Methods.
Lipatova TE, Denisova TP, Tyultyaeva LA, Kovalev EP.   +3 more
core