Results 31 to 40 of about 335,393 (290)

CLINICAL MANIFESTATIONS OF CHRONIC DISEASES ОРГАНОВ OF THE DIGESTIVE SYSTEM IN CHILDREN

, 2023
RecentlyУзбекистане , the number of childrensuffering from chronic inflammatory diseases of the digestive system has been growing in Uzbekistan органов .
Nabiyeva Zumrad Tukhtaeva
core   +1 more source

Role of Sirtuins in Modulating Neurodegeneration of the Enteric Nervous System and Central Nervous System

Frontiers in Neuroscience, 2020
Neurodegeneration of the central and enteric nervous systems is a common feature of aging and aging-related diseases, and is accelerated in individuals with metabolic dysfunction including obesity and diabetes.
Pavithra Chandramowlishwaran, Pavithra Chandramowlishwaran, Anitha Vijay, Daniel Abraham, Ge Li, Ge Li, Simon Musyoka Mwangi, Simon Musyoka Mwangi, Shanthi Srinivasan, Shanthi Srinivasan   +9 more
doaj   +1 more source

Diet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseases [PDF]

, 2023
Acrolein, a highly reactive α,β-unsaturated aldehyde, is a compound involved in the pathogenesis of many diseases, including neurodegenerative diseases, cardiovascular and respiratory diseases, diabetes mellitus, and the development of cancers
Pawel Hikisz, Jacenik, Damian, Damian Jacenik, Hikisz, Pawel   +3 more
core   +1 more source

The pathophyiological role of aminoacyl-tRNA synthetases in digestive system diseases

Frontiers in Physiology, 2022
Aminoacyl-tRNA synthetases (ARSs) catalyze the ligation of amino acids to their cognate transfer RNAs and are indispensable enzymes for protein biosynthesis in all the cells.
Wugelanmu Wusiman, Zerui Zhang, Qiang Ding, Mei Liu   +3 more
doaj   +1 more source

Surgical-site infection risk in oncologic digestive surgery [PDF]

, 2011
Surgical-site infection (SSI) is the most prevalent type of hospital infection in surgical patients and is associated with an increase in hospital stay, costs and morbidity/lethality.
PASSOS, Afonso Dinis Costa, CARVALHO, André Lopes, FOSCHINI, Milene Mitsuyuki, Costa Passos, Afonso Dinis, PERES, Stela Verzinhasse, e Castro, Paulo de Tarso Oliveira, CASTRO, Paulo de Tarso Oliveira e   +6 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Common molecular basis for MASH and hepatitis C revealed via systems biology approach

Frontiers in Oncology
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by liver inflammation and damage caused by a buildup of fat in the liver.
Yongwei Cheng, Zihao Song, Ye Liu, Xichao Xu, Dali Zhang, Yigui Zou, Liang Liu, Yinzhen Zeng, Wenwen Li, Daming Bai, Dongling Dai   +10 more
doaj   +1 more source