Results 41 to 50 of about 337,766 (290)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Multicomponent Agents for Prevention and Treatment of Digestive Diseases [PDF]

open access: yes, 2020
Introduction. In recent years, there has been a steady increase in gastroenterological diseases in many countries due to adverse environmental conditions and unsustainable nutrition.
E. V. Ferubko
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Priorities of inpatient internal care in case of chronic digestive system diseases [PDF]

open access: yes, 2015
Bakalaura darba “Pacientu aprūpes prioritātes gremošanas sistēmas hronisku saslimšanu gadījumā” mērķis – noskaidrot, aprūpes prioritātes pacientiem ar hroniskām gremošanas sistēmas saslimšanām. Pētījuma izvirzītā hipotēze – aprūpes prioritātes pacientiem
Luškovska, Ņina
core  

Diseases of the digestive system of warm-blooded horses [PDF]

open access: yes
U ovom radu će biti opisan probani sustav konja te njegove specifičnosti u odnosu na druge kategorije životinja. One uz način držanja, hranidbu i još mnogobrojne čimbenike okoline nerijetko uzrokuju razne bolesti probavnog sustava.
Lučić, Silvija
core   +4 more sources

Common molecular basis for MASH and hepatitis C revealed via systems biology approach

open access: yesFrontiers in Oncology
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by liver inflammation and damage caused by a buildup of fat in the liver.
Yongwei Cheng   +10 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Nutrition During Digestive System Diseases [PDF]

open access: yes, 2011
Bakalářská práce je zaměřena na výživu při onemocnění trávicího traktu. Definuje zánětlivá střevní onemocnění tj. Crohnovu chorobu a ulcerózní kolitidu, průjem a zácpu. Popisuje příznaky a průběh jednotlivých onemocnění.
Hladil, Zdeněk
core  

Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms

open access: yesFrontiers in Pharmacology
Dachengqi decoction (DCQD) is a traditional Chinese medicine formula consisting of three botanical drugs and one mineral drug. It has anti-inflammatory, gastrointestinal motility, and microcirculation improvement effects.
Wen Guo   +15 more
doaj   +1 more source

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