Results 201 to 210 of about 138,331 (303)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Sex- and age-specific multimorbidity networks in middle-aged inpatients: a network-based comparative study between China and the United Kingdom. [PDF]

open access: yesInnov Aging
Bao Y   +21 more
europepmc   +1 more source

Deconvolution Methods to Link Multi‐Omics Data to Cell Type‐Specific Extracellular Vesicle Abundances

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) provide non‐invasive information on cellular health and disease. Yet, with the small size of EVs and more than 200 cell types contributing EVs to the extracellular fluids, it is challenging to determine whether changes in EV‐associated lipids, RNAs, and proteins occur because of differences in expression or cell ...
Iben Skov Jensen   +2 more
wiley   +1 more source

Disease trajectory and mortality among sepsis patients: a prospective cohort study. [PDF]

open access: yesBMC Infect Dis
Li C   +7 more
europepmc   +1 more source

Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the \u3cem\u3eActa1\u3c/em\u3e H40Y Murine Model of Nemaline Myopathy [PDF]

open access: yes, 2016
Allen, Kenneth P.   +11 more
core   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

open access: yesPM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager   +3 more
wiley   +1 more source

Inquiries in the Economics of Aging [PDF]

open access: yes
Alan M. Garber   +2 more
core  

Contaminants of emerging concern in agricultural soils: Current understanding, overlooked issues, and future priorities

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Contaminants of emerging concern (CECs) in agriculture represent a growing global challenge for food safety and public health. In this review, we synthesized evidence on how substances such as pharmaceuticals, microplastics, and per‐ and polyfluoroalkyl substances (PFAS) enter soils, accumulate in crops, and affect ecological and human health. We found
Laura J. Carter   +8 more
wiley   +1 more source

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