Results 221 to 230 of about 146,043 (302)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Healthcare Costs and Trends of Multimorbidity in COPD Patients: A Population-Based Study in Singapore. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Juang YR   +11 more
europepmc   +1 more source

Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the \u3cem\u3eActa1\u3c/em\u3e H40Y Murine Model of Nemaline Myopathy [PDF]

open access: yes, 2016
Allen, Kenneth P.   +11 more
core   +1 more source

Self‐Supervised Deep Learning Framework for Rician Distribution Based Denoising and Modeling of Multi‐b Prostate Diffusion MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Convolutional neural networks (CNNs) are evaluated for improved and accelerated denoising and Rician bias correction in multi‐b DW images with simultaneous signal modeling. Methods Prostate diffusion images from 46 individuals acquired at 20 linearly distributed b‐values (bmax=2000s/mm2)$$ {b}_{\mathrm{max}}=2000\kern0.3em \mathrm{s}/{\
Mustafa Abbas   +4 more
wiley   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza   +12 more
wiley   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

open access: yesNeuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García   +7 more
wiley   +1 more source

Sex differences in dementia risk: considering underlying medical conditions. [PDF]

open access: yesAlzheimers Res Ther
Rotstein A   +3 more
europepmc   +1 more source

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