Results 231 to 240 of about 122,730 (293)

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source

Unclassified complex urogenital anomaly in a 3-year-old girl: Diagnostic and surgical challenges. [PDF]

Urol Case Rep
Manghi I, Gargano T, Ruspi F, Maffi M, Libri M, Domini M.   +5 more
europepmc   +1 more source

Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases

Movement Disorders, EarlyView.
Abstract Background Despite widespread cortical involvement in Lewy body diseases, conventional gray matter magnetic resonance imaging (MRI) shows limited sensitivity. Diffusion‐weighted MRI‐derived microstructural measures have shown utility in Alzheimer's disease, but their application across the Lewy body disease spectrum remains limited ...
Angeliki Zarkali, Ivelina Dobreva, Naomi Hannaway, Rohan Bhome, George E.C. Thomas, Steffani Carrera, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +9 more
wiley   +1 more source

Urgent Admission and Inequities in Acute Hospital Stay in Canada. [PDF]

Int J Environ Res Public Health
Basu K.
europepmc   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Trends in Mortality from Diabetes and Other Non-Communicable Diseases Among Sri Lankan Adults: A Retrospective Population-Based Study, 2004-2020/2021. [PDF]

J Clin Med
Munasinghe H, Dissanayaka P, Jayasundara M, Piyasena MP, Sivaprasad S, Nugawela MD.   +5 more
europepmc   +1 more source

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease

Neuroprotection, EarlyView.
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji, Liujia Lu, Kaidong Chen, Ruixuan Zhang, Yao Lu, Yachen Shi, Xiangming Fang   +6 more
wiley   +1 more source

Finding risk factors for dementia in patients with schizophrenia: a population-based case-control study. [PDF]

BMC Psychiatry
Ho CP, Hsu KL, Chang WC, Hsieh TC.
europepmc   +1 more source

A transient protoplast expression system for functional gene validation in sugarcane: Focus on drought response and immune pathways

New Plant Protection, EarlyView.
We developed a transient expression system for sugarcane using Guitang 42 culm, suitable for various assays such as GCaMP6‐based calcium imaging. This system revealed that ScNCED3 acts as an early drought response signal, positively regulated by ScPYL4‐12, ScOST1‐12, and ScMPK6‐11.
Dianqi Wu, Baiyang Li, Yu Gu, Yu Wang, Xinyan Wang, Shuai Zhao, Yingfeng Luo, Pan Zhao, Ting Luo, Jie Zhang, Jinlong Wang   +10 more
wiley   +1 more source

Frequency of diseases and use of medicinal plants in adults in a rural Peruvian community. [PDF]

Front Public Health
Reyna Gonzales CM, Huyhua-Gutiérrez SC, Cruz Caro O, Diaz-Manchay RJ, Tejada-Muñoz S.   +4 more
europepmc   +1 more source