Results 211 to 220 of about 121,573 (346)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Comorbidity Prevalence in Prediabetes and Type 2 Diabetes: A Cross-Sectional Study in a Predominantly Hispanic U.S.-Mexico Border Population. [PDF]

Int J Environ Res Public Health
Noriega RX, Nañez JJ, Hartmann EF, Beard JD, Sloan-Aagard CD, Thacker EL.   +5 more
europepmc   +1 more source

Characteristics of HLA and Cytokine Production in Patients with Diseases of the Genitourinary System

Serhiy Vozianov, М. Kolesnyk, V. Driianska, Oleksandr Shulyak, Tetyana Poroshina, К. Р. Нуріманов, Yu. М. Bondarenko, Olena Petryna, Viktoriia Savchenko   +8 more
openalex   +2 more sources

Introducing Novel Surgical Clinical Correlations Into an Undergraduate Medical Anatomy Course

Clinical Anatomy, EarlyView.
ABSTRACT Anatomy education is a hallmark of many preclinical medical school curricula, but students are often unable to identify the clinical relevance of anatomy and its applications. Vertical curricula that integrate clinical concepts into the preclinical basic science years and vice versa have been shown to benefit student learning and increase ...
Liam McLoughlin, Theofano Zoumpou, George P. Holan, Bao‐Ngoc Nasri, Daniel B. Jones, Jeremy J. Grachan   +5 more
wiley   +1 more source

Mortality in severe serious adverse events following heterologous and homologous prime-boost vaccination strategies for SARS-CoV-2: A retrospective cohort study. [PDF]

PLoS One
Song MC, Ha J, Park S, Kang H, Kyung T, Kim N, Kim DK, Bae K, Lee KJ, Lee E, Seok JM, Youn J.   +11 more
europepmc   +1 more source

Coordinated gene expression within sustained STAT3‐associated chromatin conformations contributes to hepatocellular carcinoma progression

Cancer Communications, EarlyView.
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang, Sumin Yoon, Hyeokjun Yang, Nayun Choi, Su‐Hyang Han, Lark Kyun Kim, Hyoung‐Pyo Kim, Jong Hoon Park, Daeyoup Lee, Kyung Hyun Yoo   +9 more
wiley   +1 more source

All-cause and cause-specific mortality attributable to educational inequalities in Spain. [PDF]

BMC Public Health
Trias-Llimós S, Riffe T, Martín U.
europepmc   +1 more source

Study on the Screening of Anti‐Osteoporosis Components in Processed Epimedium‐Based on Spectrum‐Effect Analysis

Chemistry &Biodiversity, EarlyView.
ABSTRACT Epimedium (EP) is a traditional Chinese medicine that has been used to treat osteoporosis for several years, but its mechanism of action is unclear. We used ultrahigh‐performance liquid chromatography coupled with triple–quadrupole mass spectrometry (UPLC–QQQ–MS/MS) to detect the components of raw and processed EP samples.
Jinling Liang, Jia Liu, Weixia Sun, Pan Li, Huaizhu Sun, Wenxuan Cao, Yulin Dai, Tianyang Xu, Peng Yu   +8 more
wiley   +1 more source

The Prevalence and Predictive Factors of Genitourinary Syndrome of Menopause in Postmenopausal Women: A Cross-sectional Study. [PDF]

Int J Community Based Nurs Midwifery
Mahmoudian A, Zamani Z, Mohammadzadeh F, Bahri N.   +3 more
europepmc   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

ChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang, Nataliia Lukianenko, Ja‐Hyun Baik, Yun Kyung Kim, Sungsu Lim   +4 more
wiley   +1 more source