Results 51 to 60 of about 122,841 (259)

THE CHARACTERISTICS OF THE HEALTH STATE POPULATION IN CENTRAL SERBIA

open access: yesSanamed, 2016
The aim of this study is to analyze the health status of the population in Central Serbia, in order to identify priority health problems. As a source of data, authots use the reports about diseases, conditions and injuries services for the health care ...
Radovanovic Snezana   +5 more
doaj   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

Features of territorial incidence of diseases of urogenital system of the population of Bashkortostan Republic

open access: yesRUDN Journal of Medicine, 2009
We studied the rate of the population of Bashkortostan physicians-urology and the incidence of diseases of urogenital system, depending on the type of territories.
M A Sharafutdinov
doaj  

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu   +15 more
wiley   +1 more source

Prevalence of Congenital Malformations among Babies Delivered at a Tertiary Care Hospital

open access: yesJournal of Nepal Medical Association, 2020
Introduction: Congenital malformations have emerged as a major cause of stillbirths and neonatal mortality. It is a common cause of morbidity and mortality not only in the newborn but also in childhood and beyond.
Sabina Shrestha, Anup Shrestha
doaj   +1 more source

Dynamics of disability due to diseases of the genitourinary system in Ukraine and its regions

open access: yesUrology, 2019
The dynamics of the primary recognized invalids due to diseases of the genitourinary system in general in Ukraine in two periods: 2008–2012 and 2013–2017 years are presented. The results were analyzed and compared with the indicators in five regions of the country, taking into account the areas of their composition. Official reporting data was used.
Saidakova, N.O.   +2 more
openaire   +3 more sources

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

open access: yesAdvanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu   +13 more
wiley   +1 more source

Emergency department 72-hour revisits among children with chronic diseases: a Saudi Arabian study

open access: yesBMC Pediatrics, 2018
Background Emergency Department (ED) revisits have often been used as an indicator of medical care quality. This study aimed to quantify the frequency of ED revisits within 72 h of discharge and identify its factors among children with chronic diseases ...
Anwar E. Ahmed   +9 more
doaj   +1 more source

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu   +10 more
wiley   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao   +5 more
wiley   +1 more source

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