Diseases of the musculoskeletal system

Results 11 to 20 of about 300,158 (341)

Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome

Scientific Reports, 2021
Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase
Sara Remuzgo-Martínez +30 more
doaj +1 more source

Vaspin in atherosclerotic disease and cardiovascular risk in axial spondyloarthritis: a genetic and serological study

Arthritis Research & Therapy, 2021
Background Vaspin is a novel anti-inflammatory adipokine associated with cardiovascular (CV) disease and inflammation in chronic inflammatory conditions different from axial spondyloarthritis (axSpA). Given the high incidence of CV disease (mainly due to
Javier Rueda-Gotor +30 more
doaj +1 more source

Irisin as a Novel Biomarker of Subclinical Atherosclerosis, Cardiovascular Risk and Severe Disease in Axial Spondyloarthritis

Frontiers in Immunology, 2022
IntroductionPatients with axial spondyloarthritis (axSpA) have a high disease burden mainly due to the rheumatic disease itself, and also exhibit accelerated atherosclerosis, that leads to a higher incidence of cardiovascular (CV) disease.
Sara Remuzgo-Martínez +37 more
doaj +1 more source

Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis

Scientific Reports, 2021
Cytokines signalling pathway genes are crucial factors of the genetic network underlying the pathogenesis of Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular condition.
Diana Prieto-Peña +29 more
doaj +1 more source

Predicting survival of patients with bone metastasis of unknown origin

Frontiers in Endocrinology, 2023
PurposeBone metastasis of unknown origin is a rare and challenging situation, which is infrequently reported. Therefore, the current study was performed to analyze the clinicopathologic features and risk factors of survival among patients with bone ...
Ying Ren +27 more
doaj +1 more source

Omentin: a biomarker of cardiovascular risk in individuals with axial spondyloarthritis

Scientific Reports, 2020
Cardiovascular (CV) disease is the main cause of mortality in axial spondyloarthritis (axSpA). CV risk is enhanced by dysregulation of adipokines. Low omentin levels were associated with metabolic dysfunction and CV disease in conditions different from ...
Fernanda Genre +24 more
doaj +1 more source

BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis

Scientific Reports, 2021
BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF GCTGT>A a shared insertion-deletion ...
Diana Prieto-Peña +28 more
doaj +1 more source

The Digital Twin: A Potential Solution for the Personalized Diagnosis and Treatment of Musculoskeletal System Diseases

Bioengineering, 2023
Due to the high prevalence and rates of disability associated with musculoskeletal system diseases, more thorough research into diagnosis, pathogenesis, and treatments is required.
Tianze Sun +7 more
doaj +1 more source

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources

Reduced hypothalamic-pituitary-adrenal axis activity in chronic multi-site musculoskeletal pain : partly masked by depressive and anxiety disorders [PDF]

, 2014
Peer reviewedPublisher ...
Dekker, Joost +6 more
core +4 more sources

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