Results 111 to 120 of about 1,599,144 (366)
The effect of various drugs on experimentally induced ulcers in immobilized rats [PDF]
Experiments related to the importance of functional disorders in the central nervous system in connection with stomach diseases were performed on Wistar rats.
Schramm, H.
core +1 more source
Extracellular proteases and their inhibitors ingenetic diseases of the central nervous system [PDF]
, 2017 Cumulative evidence has shown that a delicate balance between serine proteases and their inhibitors is crucial for normal functioning of several biological pathways.
Colleaux, Laurence +4 more
core
Cache valley virus in a patient diagnosed with aseptic meningitis [PDF]
, 2013 Cache Valley virus was initially isolated from mosquitoes and had been linked to central nervous system-associated diseases. A case of Cache Valley virus infection is described.
Hull, Rene +8 more
core +2 more sources
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Editorial: Non-coding RNAs in diseases of the nervous system. [PDF]
Front Cell Neurosci, 2023 Reschke CR, Chowdhury EH, Lee AYW.
europepmc +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Creutzfeldt-Jakob disease: recent developments [version 1; referees: 2 approved]
F1000Research, 2017 Creutzfeldt-Jakob disease (CJD) is a rare prion disorder that has been the subject of both professional and public interest following the identification of variant CJD as a zoonotic disorder.
Graeme Mackenzie, Robert Will
doaj +1 more source
P53 protein and the diseases in central nervous system. [PDF]
Front Genet, 2022 Lei L, Lu Q, Ma G, Li T, Deng J, Li W.
europepmc +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source