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Gastrointestinal symptoms are frequent in acute adrenal insufficiency. Although digestive symptoms can significantly reduce quality of life, they are rarely described in patients with treated chronic adrenal insufficiency (CAI).
L. Quénéhervé+10 more
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Effects of oxidative stress on hepatic encephalopathy pathogenesis in mice
Oxidative stress plays a crucial role in the pathogenesis of hepatic encephalopathy (HE), but the mechanism remains unclear. GABAergic neurons in substantia nigra pars reticulata (SNr) contribute to the motor deficit of HE.
Yunhu Bai+12 more
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Criteria for diagnosis and classification of vascular cognitive impairment
Vascular cognitive impairment (VCI) is a very diverse group of conditions that differ in etiopathogenesis, severity, clinical picture, dynamics and severity of functional disorders.
A. Y. Emelin, V. Y. Lobzin
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BYSL, which encodes the human bystin protein, is a sensitive marker for astrocyte proliferation during brain damage and inflammation. Previous studies have revealed that BYSL has important roles in embryo implantation and prostate cancer infiltration ...
Zhuang Sha+19 more
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Background Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis. However, there are no effective targeted therapies for glioma patients.
Chenglong Yue+8 more
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β-catenin-mediated YAP signaling promotes human glioma growth
Background Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression.We and others find that YAP is up-regulated in human gliomas and associated with worse prognosis
Yan Wang+8 more
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Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness
Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1.
Bettina Zierfuss+15 more
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Illness perception in patients with chronic migraine: cognitive, emotional and behavioral aspects
In patients with chronic migraine (CM), the illness perception includes three main aspects: cognitive (thoughts, beliefs, attitude towards pain), emotional (mood) and behavioral (pain coping strategies). The patient’s perception affects the course of CM,
V. A. Golovacheva+3 more
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The Influence of Heredity on Disease, with Special Reference to Tuberculosis, Cancer and Diseases of the Nervous System [PDF]
William S. Church
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