Results 31 to 40 of about 1,542,715 (367)

Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung’s disease

Scientific Reports, 2020
In Hirschsprung’s disease (HSCR), postoperative course remains unpredictable. Our aim was to define predictive factors of the main postoperative complications: obstructive symptoms (OS) and Hirschsprung-associated enterocolitis (HAEC).
Anne Dariel, Lucie Grynberg, Marie Auger, Chloé Lefèvre, Tony Durand, Philippe Aubert, Catherine Le Berre-Scoul, Aurélien Venara, Etienne Suply, Marc-David Leclair, Philine de Vries, Guillaume Levard, Benoit Parmentier, Guillaume Podevin, Françoise Schmitt, Véronique Couvrat, Sabine Irtan, Erik Hervieux, Thierry Villemagne, Hubert Lardy, Carmen Capito, Cécile Muller, Sabine Sarnacki, Jean-François Mosnier, Louise Galmiche, Pascal Derkinderen, Hélène Boudin, Charlène Brochard, Michel Neunlist   +28 more
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Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway

Scientific Reports, 2017
The RAS signaling pathway is hyperactive in malignant glioma due to overexpression and/or increased activity. A previous study identified that RASD1, a member of the RAS superfamily of small G-proteins, is a significantly dysregulated gene in ...
Shangfeng Gao, Lei Jin, Guangping Liu, Peng Wang, Zonghan Sun, Yujia Cao, Hengliang Shi, Xuejiao Liu, Qiong Shi, Xiuping Zhou, Rutong Yu   +10 more
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Digestive symptoms in daily life of chronic adrenal insufficiency patients are similar to irritable bowel syndrome symptoms

Scientific Reports, 2021
Gastrointestinal symptoms are frequent in acute adrenal insufficiency. Although digestive symptoms can significantly reduce quality of life, they are rarely described in patients with treated chronic adrenal insufficiency (CAI).
L. Quénéhervé, D. Drui, J. Blin, M. Péré, E. Coron, G. Barbara, M. R. Barbaro, B. Cariou, M. Neunlist, D. Masson, K. Bach-Ngohou   +10 more
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Bacteria Wear ICG Clothes for Rapid Detection of Intracranial Infection in Patients After Neurosurgery and Photothermal Antibacterial Therapy Against Streptococcus Mutans

Frontiers in Bioengineering and Biotechnology, 2022
Bacterial infection is one of the most serious physiological conditions threatening human health. There is an increasing demand for more effective bacterial diagnosis and treatment through non-invasive approaches.
Long Zhang, Long Zhang, Long Zhang, Deyun Zhang, Hai Tang, Yufu Zhu, Yufu Zhu, Hongmei Liu, Hongmei Liu, Hongmei Liu, Rutong Yu, Rutong Yu   +11 more
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Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission

Redox Biology, 2022
Mitochondria play an essential role in pathophysiology of both inflammatory and neuropathic pain (NP), but the mechanisms are not yet clear. Dynamin-related protein 1 (Drp1) is broadly expressed in the central nervous system and plays a role in the ...
Kun-Long Zhang, Shu-Jiao Li, Xue-Yin Pu, Fei-Fei Wu, Hui Liu, Rui-Qing Wang, Bo-Zhi Liu, Ze Li, Kai-Feng Li, Nian-Song Qian, Yan-Ling Yang, Hua Yuan, Ya-Yun Wang   +12 more
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Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]

, 2019
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
core   +1 more source

The role of motile cilia in the development and physiology of the nervous system

Philosophical Transactions of the Royal Society of London. Biological Sciences, 2019
Motile cilia are miniature, whip-like organelles whose beating generates a directional fluid flow. The flow generated by ciliated epithelia is a subject of great interest, as defective ciliary motility results in severe human diseases called motile ...
Christa Ringers, E. W. Olstad, Nathalie Jurisch-Yaksi   +2 more
semanticscholar   +1 more source

Clinical application of sialic acid (II) Sialic acid contents in cerebro-spinal fluid of patients suffering from the disease of the central nervous system [PDF]

, 1959
It is well known that human serum contains some sialic acid and its contents increase markedly in the blood serum of the patients bearing malignant tumors.
Kanbayashi, Tsuneo, Kawakami, Hiroshi, Saito, Kunio, Yamaguchi, Michiya   +3 more
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Effects of oxidative stress on hepatic encephalopathy pathogenesis in mice

Nature Communications, 2023
Oxidative stress plays a crucial role in the pathogenesis of hepatic encephalopathy (HE), but the mechanism remains unclear. GABAergic neurons in substantia nigra pars reticulata (SNr) contribute to the motor deficit of HE.
Yunhu Bai, Kenan Li, Xiaodong Li, Xiyu Chen, Jie Zheng, Feifei Wu, Jinghao Chen, Ze Li, Shuai Zhang, Kun Wu, Yong Chen, Yayun Wang, Yanling Yang   +12 more
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Criteria for diagnosis and classification of vascular cognitive impairment

Неврология, нейропсихиатрия, психосоматика, 2022
Vascular cognitive impairment (VCI) is a very diverse group of conditions that differ in etiopathogenesis, severity, clinical picture, dynamics and severity of functional disorders.
A. Y. Emelin, V. Y. Lobzin
doaj   +1 more source