Results 31 to 40 of about 716,091 (301)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

ON THE STUDY OF DISEASES OF THE NERVOUS SYSTEM. [PDF]

Brain, 1903
n ...
openaire   +3 more sources

Effect of hypovitaminosis D on the characteristics of chronic tension-type headache in women

Неврология, нейропсихиатрия, психосоматика, 2022
There is a growing body of evidence linking hypovitaminosis D with the prevalence and severity of various pain conditions. The effect of vitamin D levels on chronic tension type headache (CTTH) is almost unexplored.Objective: to investigate the effect of
A. A. Koloskova, O. V. Vorobyeva
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Trauma and Diseases of the Nervous System [PDF]

The Journal of Nervous and Mental Disease, 1904
n ...
openaire   +2 more sources

Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction

Experimental Hematology & Oncology
Background Glioblastoma is a highly aggressive and devastating primary brain tumor that is resistant to conventional therapies. Oncolytic viruses represent a promising therapeutic approach for glioblastoma by selectively lysing tumor cells and eliciting ...
Yufu Zhu, Xuefeng Zhang, Jiaqi Jin, Xiaoqian Wang, Yang Liu, Jian Gao, Diancheng Hang, Lin Fang, Hengzhu Zhang, Hongmei Liu   +9 more
doaj   +1 more source

Assessment of Appetite-Regulating Hormones Provides Further Evidence of Altered Adipoinsular Axis in Early Psychosis

Frontiers in Psychiatry, 2020
It has been found that antipsychotic-naïve patients with first-episode psychosis (FEP) present with impaired hormonal regulation of appetite in terms of low leptin and high insulin levels (the adipoinsular axis).
Michał Lis, Bartłomiej Stańczykiewicz, Lilla Pawlik-Sobecka, Agnieszka Samochowiec, Artur Reginia, Błażej Misiak   +5 more
doaj   +1 more source

Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response

Communications Biology, 2022
Using Epstein-Barr virus (EBV) infection of human B cells, the importance of peroxisomal very long-chain fatty acid transport involving ABCD1 in viral infection and host defence is elucidated and applicable also to other herpes- and coronaviruses.
Isabelle Weinhofer, Agnieszka Buda, Markus Kunze, Zsofia Palfi, Matthäus Traunfellner, Sarah Hesse, Andrea Villoria-Gonzalez, Jörg Hofmann, Simon Hametner, Günther Regelsberger, Ann B. Moser, Florian Eichler, Stephan Kemp, Jan Bauer, Jörn-Sven Kühl, Sonja Forss-Petter, Johannes Berger   +16 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Disease representation in children and its mediating role in the therapeutic work with patient children [PDF]

Национальный психологический журнал, 2015
In the course of treating a serious illness, a person is faced with questions related not only to the medical side of treatment, but also with the realizing the sense of the events. This is equally true for both oncology adults and for children.
Arkady N. Kharkovskiy
doaj   +1 more source