Results 221 to 230 of about 181,687,172 (282)

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

District-level ecological analysis of the association between stunting and infectious diseases among children under 2 years in Rwanda, 2020-2024. [PDF]

Front Public Health
Ntawuyirushintege S, Mohamed NS, Ahmed A, Semakula M, Remera E, Tediosi F, Wyss K.   +6 more
europepmc   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Posters from the Canadian Society of Respiratory Therapists Annual Education Conference [PDF]

, 2018
Canadian Society of Respiratory Therapists
core  

Standardising terminology in routine electronic health records for respiratory endpoints: why we still can't agree. [PDF]

Thorax
Lahousse L, Håkansson KEJ, Balasubramanian A, van Boven JFM, Gershon AS, Hochberg CH, Joos GF, Kocks JWH, Lewis A, Navaratnam V, Nyberg F, Stanojevic S, King MT, Tibble H, Vanfleteren L, Weinreich UM, Verhamme K, Quint JK.   +17 more
europepmc   +1 more source

Risks of adverse respiratory outcomes in adults with cancer over the course of survivorship compared with cancer-free individuals: a matched cohort study using linked English electronic health records. [PDF]

EClinicalMedicine
Andresen K, Carreira H, Forbes H, Bowen L, Quint JK, Williamson E, Bhaskaran K.   +6 more
europepmc   +1 more source