Results 41 to 50 of about 36,615 (199)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Conflict Management, Transitional Justice and De-radicalization – Different, but common goals

Journal for Deradicalization, 2016
The aim of this working paper is to explore common issues between the process of reconciliation in post-conflict societies, negotiations and the renouncement of violent means.
Anna Mühlhausen
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Laser Metal Deposited Ti4822 Hollow Pipe: Experimental and Computational Modelling Study

Advanced Engineering Materials, EarlyView.
Laser metal deposition (LMD) of a crack‐free built Ti4822 alloys is challenging. This article reports outstanding characteristics of a hollow pipe that is built with LMD technology when a predicted, nontransformation substrate temperature of 800 °C is used.
Sadiq A. Raji, Monnamme Tlotleng, Samuel Skhosane, Lehlogonolo R. Kanyane, Abimbola P. I. Popoola, Sisa L. Pityana   +5 more
wiley   +1 more source

Unveiling Shadows: Tracking Youth Disengagement from the Church [Menyingkap Bayangan: Melacak Penyebab Keterpisahan Kaum Muda dari Gereja]

Diligentia: Journal of Theology and Christian Education
The idea of human belief in curses poses a problem for the curse part in Psalms. Problem of misunderstanding the curses part of Psalm 83:1-19 arises among believers.
Samuel Ntsanwisi
doaj   +1 more source

A VUCA ACTION FRAMEWORK FOR A VUCA ENVIRONMENT. LEADERSHIP CHALLENGES AND SOLUTIONS [PDF]

Journal of Defense Resources Management, 2016
The 1990 coinage describing the surrounding environment as volatile, uncertain, complex and agile (VUCA) is becoming a cliché in the absence of a more profound analysis.
Aura Codreanu
doaj  

The Pathway to Defection from Extremist Groups – Confronting the Disengagement Process of a Jihadi Foreign Fighter and a Right-Wing Extremist

sozialpolitik.ch, 2019
The aim of our article is to analyse the disengagement process of a Swiss returnee from Syria and the emergence of dissonances during his involvement with the Islamic State (IS) and to compare this evolution to the pathway of a right-wing extremist ...
Miryam Eser Davolio, Carole Villiger
doaj   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Is Young's Modulus a Critical Coating Property Determining Fouling‐Release Performance of Marine Coatings?

Advanced Engineering Materials, EarlyView.
The release of foulers from protective marine coatings is determined by several interrelated material properties, including the strength of Young's modulus, the flexibility of chain segments, the surface free energy, and the magnitude of hydrodynamic stress.
Johann C. Schaal, Andreas Brinkmann, Andreas Hartwig   +2 more
wiley   +1 more source