Results 51 to 60 of about 6,135,521 (362)

Moral disengagement and the motivational gap in climate change [PDF]

, 2019
Although climate change jeopardizes the fundamental human rights of current as well as future people, current actions and ambitions to tackle it are inadequate.
Diependaele, Lisa, Peeters, Wouter, Sterckx, Sigrid   +2 more
core   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Prisoners’ gang-related activity: the importance of bullying and moral disengagement [PDF]

, 2009
Gang-related activity can have a significant impact on the effective management of prisons in the UK, yet little is known about the characteristics of the prisoners involved.
James, M., James, M., Moir, A., Moir, A., Wood, J., Wood, J.   +5 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

From exhaustion to disengagement via self-efficacy change: Findings from two longitudinal studies among human services workers

Frontiers in Psychology, 2016
This longitudinal research examined the relationship direction between burnout components (exhaustion and disengagement) within the context of personal resources measured by self-efficacy and social support.
Anna eRogala, Kotaro eShoji, Aleksandra eLuszczynska, Aleksandra eLuszczynska, Anna eKuna, Carolyn eYeager, Carolyn eYeager, Charles eBenight, Charles eBenight, Roman eCieslak, Roman eCieslak   +10 more
doaj   +1 more source

Increased attentional control for emotional distractors moderates the use of reflective pondering in times of life stress: a prospective study [PDF]

, 2012
According to the response styles theory, rumination is a cognitive response to a stressor with repetitive and self–focused attention on a negative mood state.
De Raedt, Rudi, Goubert, Liesbet, Koster, Ernst, Vanderhasselt, Marie-Anne   +3 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

From Citizenship Pressure to Pro-Group Unethical Behavior: The Dual-Stage Moderating Role of Self-Serving Political Will

Behavioral Sciences, 2023
Drawing upon social cognitive theory, our study proposes a dual-stage moderated mediation model that utilizes moral disengagement as the mediator and self-serving political will as the moderator to investigate whether, how, and when team-oriented ...
Hantai Zhang, Minqiao Hu, Xin Liu, Xuan Yu, Jinyu Xie   +4 more
doaj   +1 more source

An Examination of Student Disengagement and Reengagement from an Alternative High School [PDF]

, 2019
Each year, 20% of U.S. students drop out of high school (Balfanz, Bridgeland, Bruce, & Fox, 2013). There is an abundance of research on student behaviors from researchers who explored the process of student disengagement from school (Bowers, Sprott ...
Flores, Marina Escamilla, Graham Brown, Casey   +1 more
core   +1 more source

When the going gets tough: the “Why” of goal striving matters [PDF]

, 2013
No prior research has examined how motivation for goal striving influences persistence in the face of increasing goal difficulty. This research examined the role of self-reported (Study 1) and primed (Study 2) autonomous and controlled motives in ...
Amiot, Bandura, Bargh, Bentler, Carver, Deci, Deci, Dweck, Fishbach, Friedman, Gaudreau, Gaudreau, Gauvin, Gollwitzer, Goss, Haase, Hayduk, Hodgins, Johnson, Klein, Koestner, Koestner, Lazarus, Lazarus, Levesque, Locke, Locke, Louro, Masicampo, Masicampo, McGregor, Moller, Ntoumanis, Preacher, Radel, Ratelle, Ryan, Ryan, Sheldon, Sheldon, Sheldon, Sheldon, Skinner, Smith, Smith, Smith, Strack, Weinberg, Williamson, Wrosch, Zimmerman   +50 more
core   +4 more sources