Results 151 to 160 of about 54,604 (264)

Impact of low temperature on the efficacy of chlorous acid water and sodium hypochlorite solution for inactivating avian influenza virus on material surfaces. [PDF]

PLoS One
Morita T, Elsayed AMA, Hirakawa R, Lawal-Ayinde BM, Akita T, Yamamoto A, Higashiura A, Nomura T, Horiuchi I, Goda H, Tanaka J, Sakaguchi T.   +11 more
europepmc   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Persistence as a microbial survival strategy against disinfectants

, 2018
Antimicrobial resistance is a major threat to human health. The prevalence of multi-drug resistant (MDR) bacteria is predicted to increase in the future requiring robust control strategies.
Nordholt, Niclas
core  

Reduced susceptibility to triclosan and proposed epidemiological cut-off values for disinfectants and heavy metals in Escherichia coli isolated from Thai tilapia farms: Implications for One Health antimicrobial resistance surveillance. [PDF]

Vet World
Thaotumpitak V, Sripradite J, Anuntawirun S, Roongrojmongkhon N, Hinthong W, Jeamsripong S.   +5 more
europepmc   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

<i>In Vitro</i> Antifungal Activity of Commonly Used Antiseptics and Disinfectants Against <i>Candida auris</i> Isolates. [PDF]

Medeni Med J
Habip Z, Koçoğlu ME, Güneysu Yarar B, Özmen M, Çetin Ş, Özekinci T.   +5 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

The impact of bedding materials and disinfectants on udder health and mastitis control in dairy cows [PDF]

This study investigates the influence of disinfectants applied in bedding areas on mastitis prevalence in dairy farming, emphasizing the critical relationship between bedding materials, disinfectants, and udder health indicators.
Tosun, Hİ, Ahmadi, F, Shahedani, MS
core  

Effects of three feed disinfectants on microbial population and nutritional value of broiler diets. [PDF]

Poult Sci
Janfadah A, Madani SA, Mohammadian MR, Hashemian SMM.   +3 more
europepmc   +1 more source